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Pharm block 4 > Hypo-pit drugs > Flashcards

Hypo-pit drugs Flashcards

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1
Q

Sermorelin MOA

A

synthetic GHRH

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2
Q

Somatotropin/ Somatrem MOA

A

Synnthetic GH

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3
Q

Sermorelin/ somatoropin/ somatrem indications

A

growth failure, praider willi, turners, short bowel syndrome

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4
Q

sermorelin/ somatrotropin/ somatrem contraindications

A

peds pts with closed plates, intracranial lesions, malignancy, diabetic retinopathy

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5
Q

sermorelin, somatorpin/ somatrem AE

A

leukemia, hypothyroid, insulin resistance, arthralgia, inc cyp 450

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6
Q

Mecasermin MOA

A

recombinant IGF-1

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7
Q

Mecasermin indications

A

laron dwarfism- mutations in GH receptor

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8
Q

Octeotide/ Lanreotide MOA

A

somatostatin analogue, inhibits GH

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9
Q

Octeotride/ lanreotide ind

A

pit adenoma, carcinoid crisis, VIP-oma, GI bleed (stops acid production)

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10
Q

Octeotride/ Lanreotide AE

A

GI: nausea/ comiting/ cramps
cardio: sinus brady cardia, conduction problems
gallstones

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11
Q

Pegvisomant MOA

A

GH receptor antagonist

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12
Q

Pegvisomant indications

A

refractive acromegaly

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13
Q

pegvisomant AE

A

increased adenoma size, inc aminotrnasferase

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14
Q

Gonadotrophs MOA and names

A

MOA: replace FSH and LH

Menotorpin (menopausal women), hCG, urofollitropin, follitropin

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15
Q

Gonadotophs indications

A

start ovulation for women with: hypo hypogonadism, PCOS.

male infertility for hypog/ hypog

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16
Q

Gonadotrophs contra

A

endocrine disorders other than anovulation, gonadal fialur, tomrs, ovarian cyst/ enlargement, pregnancy

Pharm block 4 (5 decks)

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