diabetes drugs Flashcards
aspart
rapid actin insulin (lasts 2-4 hrs)
Lispro
rapid actin insulin (lasts 2-4 hrs)
glulisine
rapid actin insulin (lasts 2-4 hrs)
NPH
intermediate acting insulin (twice daily dose)
Glargine
long acting insulin (once daily dosing)
Detmir
long acting insulin (6-24 hr lasting)
Sulfonylureas
chlorporopamide, tolbutamide, glimepiride, glipizide, glyburide (long term helping insulin secretino by blocking K channel
Meglitinides
Repaglinide, nateglinide (short term inhibition of K+ channel and lowering o fpost prandial)
thiozolidinediones
pioglitazone, rosiglitazone (pparg agonist..increase insulin senesiityvity
alpha glucosidase inhibitor
acarbose, miglitol (decrease glucose asorption)
incretin mimetics
exanatide, liraglutide (glp 1 analog…helps insulin release)
dpp-IV inhiitors
sitagliptin/ saxagliptin… inhibiting enzyme that breaks down GLP1
Prmalintide
amylin mimetic (decreases glucagon, increases satiety…helps weight loss)
SGLT2 inhibitors
canagliflozin, dpaagilflozin…inhibits reabsorption of glucose in kidney
Bromocriptine
dop antagonist….helps hypothalamic clock