Hypnotics & Anxiolytics Flashcards
Side effects of acute BZD use
- non selective depressive activity
- sedation if used for anxiolysis
- poor motor coordination
- amnesia
- decreased REM sleep
- effects potentiated by alcohol
Side effects of chronic BZD use
Withdrawal: rebound anxiety (due to GABA receptor adaptation)
Contraindications to BZD use
hepatic impairment
Panic disorder
recommended tx + not recommended
Recommended:
SSRI, TCAs (Imipramine, Clomipramine)
Not recommended: Benzo
Generalised anxiety disorder
recommended tx + not recommended
Recommended:
SSRI, SNRI
Not recommended: Benzo (except short term during crisis)
OCD
recommended tx + not recommended
Recommended:
SSRI
Not recommended:
TCA, SNRI, serotonin reuptake inhibitor, MAOI, Benzo
PTSD
recommended tx
Recommended:
SSRI
+ hypnotic if sleep disturbance
Acute anxiety/adjustment disorder
recommended tx
Benzos (diazepam, tamazopam)
Social anxiety disorder
recommended tx
Venlafaxine (SNRI)