Hypertrophic Obstructive Cardiomyopathy

Question 1

Definition of Hypertrophic Obstructive Cardiomyopathy

Answer 1

• LVOT obstruction from asymmetric septal hypertrophy

Question 2

Aetiology of Hypertrophic Obstructive Cardiomyopathy

Answer 2

• AD inheritance
• β-myosin heavy chain mutation commonest

Question 3

Signs and Symptoms of Hypertrophic Obstructive Cardiomyopathy

Answer 3

• Signs/symptoms include angina, dyspnoea, palpitations, AF, WPW, VT, exertional syncope, sudden death, jerky pulse, double apex beat, harsh ESM at LLSE, systolic thrill and S4.

Question 4

Investigation of Hypertrophic Obstructive Cardiomyopathy

Answer 4

• ECG
  
  • LVH/LAD/L strain
  • Ventricular ectopics
  • VT
  • VF
• ECHO
  
  • ASH