Hyperthermia Flashcards
1
Q
how is malignant hyperthermia treated?
A
cool body temperature
dantrolene
2
Q
describe the pathophysiology of malignant hyperthermia?
A
increase in core body temperature > 40 + significant CNS dysfunction in response to excessive release of Ca from the sarcoplasmic reticulum in skeletal muscle
most often due to administration of anaesthetics
3
Q
what are causative agents of malignant hyperthermia?
A
halothane
suxamthonium
antipsychotics (neuroleptic malignant syndrome)
4
Q
what are the features of malignant hyperthermia?
A
rigidity
core body temp > 40
elevated CK
contractures (with halothane and caffeine)
