Hypertension Flashcards
How do angiotensin receptor blockers work?
They bind to angiotensin receptors to prevent vasoconstriction and the release of aldosterone.
How do ACE inhibitors work?
They block the conversion of angiotensin I to angiotensin II by stopping the Angiotensin Converting Enzyme (ACE) in the lungs which stops the renin-angiotensin-aldosterone system and preventing vasoconstriction.
How do calcium channel antagonists work?
They prevent the movement of calcium into the cardiac and smooth muscle cells and interfere with the muscles ability to contract.
How do beta-blockers work?
They decrease the release of renin to prevent vasoconstriction and cardiac contraction and increase blood flow to the kidneys.
How do alpha-blockers work?
They inhibit post-synaptic alpha-adrenergic receptors which block the action of NaCl and adrenaline. This decreases sympathetic tone and causes vasodilation.
Now do thiazide-like diuretics work?
They increase the excretion of sodium and water from the kidneys which affects blood volume and lowers blood pressure.
How do vasodilators work?
These are for emergencies and cause direct vasodilation.
What are examples of ACE inhibitors?
- Captopril
- Enalapril
- Moexipril
- Ramipril
What are examples of angiotensin receptor blockers?
- Cardesartan
- Eprosartan
- lrbesartan
- Olmesartan
What are examples of calcium channel blockers?
- Amlodipine
- Felodipine
- Isradipine
- Nicardipine
What are examples of Beta-blockers?
- Atenolol
- Metaprolol
- Propanolol
- Sotalol
What are examples of alpha-blockers?
- Prozosin
- Terazosin
- Doxazosin
What are examples of thiazide-like diuretics?
- Bendroflumethiazide
What are examples of vasodilators?
- Diazoxide
- Hydrazine
