Hypertension Flashcards

1
Q

What is stage 1 hypertension

A

140/90 - 160/100

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2
Q

What is stage 2 hypertension

A

160/100-180/120

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3
Q

What is stage 3 hypertension

A

More than 180

More than 120

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4
Q

Hypertension diagnosis

A
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5
Q

Hypertension NICE guidelines

A
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6
Q

Overview

A
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7
Q

Hypertension in pregnancy

A

1st line - labetolol
(100mg BD) - usual dose is 200mg daily in 2 divided doses. Take with food

2nd line - nifedipine

3rd line - methyldopa

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8
Q

What is used for hypertension when breastfeeding |

A

Enalapril maleate

(monitor renal function and potassium)

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9
Q

What is the target in pregnancy

A

140/90

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10
Q

What is the target in renal disease (CKD)

A

140/90

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11
Q

What is the target in Renal disease and diabetes together

A

130/80

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12
Q

Type 1 diabetes target

A

135/85

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13
Q

Same day specialist referral

A

180/120

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14
Q

Age less than 80

A

140/90

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15
Q

Age 80 or more

A

150/90

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16
Q

What betareceptors are found in the heart

A

B1

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17
Q

What Beta receptors are found in the lungs

A

B2

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18
Q

Which ones have less coldness and less bradycardia

A

ICE PACO

Pindolol
Acebutalol
Celiprolol
Oxprenolol

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19
Q

Water soluble beta blockers

A

CANS

Celiprolol
Atenolol
Nadolol
Sotalol

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20
Q

Cardioselectove beta blockers (less effect on B2, less respiratory problems

A

B A MAN

Bisoprolol
Atenolol
Metropolol
Nebivolol

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21
Q

Long duration of action

A

BACN

Bisoprolol
Atenolol
Celiprolol
Nadolol

Give ONCE daily
Rest are short duration of action

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22
Q

Name some SE of betablockers

A

Fatigue
Coldness
Sleep disturbances
Bradycardia
Hypo/hyperkalaemia
Masks symptoms of hypo
Look out for asthmatic patients

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23
Q

What respiratory issue do beta blockers cause

A

Bronchospasm - keep an eye out for asthmatic patients, those with COPD etc

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24
Q

What can beta blockers do to heart rate

A

Bradycardia - my be countered with atropine sulphate

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25
Q

What do beta blockers interact with that increases risk of hypotension

A

Verapamil

26
Q

What can labetalol cause

A

Liver damage

27
Q

What BB is used in migraines and anxiety

A

Propranolol

28
Q

What BB is used in glaucoma

A

Timolol

29
Q

What BB is used in thyrotoxicosis

A

Propranolol

30
Q

What are some contraindications with BB

A

Asthma, COPD and bronchospasm (if no alternative then cardioselective)

Marked bradycardia

2nd and 3rd degree AV block

Uncontrolled HF

31
Q

What 2 CCBs should not be given in HF

A

Verapamil and Diltiazem

32
Q

What are some examples of CCBs

A

Amlodipine
Felodipine
Lacidipine
Lercanidipine

33
Q

Common SE of verapamil

A

Constipation

34
Q

Should diltiazem be prescribed by same brand

A

yes

35
Q

What can sudden withdrawal of CCBs cause

A

Angina

36
Q

Side effects of CCBs

A

Ankle swelling, dizziness, flushing, headaches, postural hypotension

37
Q

Name 2 thiazide diuretics

A

Bendroflumethiazide, indapamide

38
Q

What is mechanism of thiazide d

A

Inhibit sodium reabsorption

39
Q

When should thiazide d be given

A

In the morning to avoid getting up during the night

40
Q

What side effects can thiazide d cause

A

exacerbate diabetes, gout, constipation, postural hypotension

41
Q

When should thiazide d be avoided

A

Severe liver disease

42
Q

What are 2 examples of loop diuretics

A

Furosemide, bumetanide

43
Q

Where are loop diuretics used

A

Pulmonary oedema

44
Q

How quickly do loops act

A

within the hour

45
Q

Can they interfere with sleep

A

no

46
Q

Where are loop contraindicated

A

hyponatremia, hypokalameia and liver chirrosis

47
Q

What can loops cause

A

tinnitus or deafness

48
Q

What 2 can turn urine blue

A

Furosemide

Triamterene

49
Q

Give an example of potassium sparing diuretics

A

Spironolactone

50
Q

What should you not give with spironolactone

A

Potassium - severe hyperkalaemia

51
Q

What can cause gynaecomastia

A

Spironolactone

52
Q

How does ACE work

A

Inhibits conversion of angiotensin 1 to 2

53
Q

What are ACEs and Aliskiren contraindicated

A

Diabetes and egfr less than 60

54
Q

Is first dose hypotension possible with ACE

A

Yes

55
Q

What are the common side effects ACE

A

Dry cough (due to bradykinin), GI reactions, alopecia, angiodema

56
Q

Should you use NSAIDs with ACE

A

No

57
Q

What can ACE and potassium sparing diuretics cause

A

Hyperkalaemia

58
Q

When should you stop use of ACEs

A

Signs of liver damage

59
Q

Are ARBs less likely to cause dry cough

A

Yes

60
Q

Should ARBs and ACEs be avoided in pregnancy

A

Yes

61
Q

Can ARBs cause hyperkalaemia

A

Yes