ACS - acute coronary syndrome Flashcards

1
Q

What is ACS

A

A spectrum of conditions which include MI with or without ST segment elevation

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2
Q

How are unstable angina and NSTEMI caused

A

Partial blockage of a blood vessel

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3
Q

Where is myocardial necrosis more evident, NSTEMI or STEMI

A

STEMI

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4
Q

What is STEMI

A

Complete blockage of blood vessel = causes irreversible necrosis of heart muscle. It is the worse form of ACS

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5
Q

What levels can we measure to detect heart attack

A

Troponin levels

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6
Q

Symptoms of ACS

A

Chest pain

Can spread to left arm

Can be triggered by physical exertion or stress

Stops within a few mins of resting

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7
Q

What is stable angina

A

Predictable, symptoms occur on activity, stop when resting

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8
Q

What is unstable angina

A

Unpredictable, chest pain is still there on resting and is for longer and more severe

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9
Q

What is the initial management of ACS

A
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10
Q

Why is GTN, iv opioids e.g. morphine given ASAP in initial management of ACS?

A

Pain relief

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11
Q

Why is Aspirin given in initial management of ACS?

A

To limit clot size and allow blood to flow

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12
Q

Why is oxygen given in initial management of ACS?

A

Only if needed

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13
Q

In what instance would insulin be given in initial management of ACS

A

If glucose is higher than 11mmol/l

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14
Q

What is the secondary prevention of ACS

A
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15
Q

Why are nitrates useful in angina

A

They are coronary vasodilators

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16
Q

What are the three common forms of GTN

A

Patches, tablets, sprays

17
Q

What are some side effects of nitrates

A

Flushing, headaches and postural hypotension

18
Q

How long does GTN last for

A

20-30 mins

19
Q

How is the GTN spray used

A

1 tablet (or 1-2 sprays) and wait 5 mins. Then do the second dose and wait 5 mins

Seek medical attention if still hasn’t worked

20
Q

When do you need long term prophylaxis

A

When GTN is being used more than twice a week

21
Q

What strength GTN tablets are used

22
Q

How should tablets be supplied

A

In glass containers (no more than 100 tablets) in foil line caps

23
Q

How many weeks after should they be discarded

24
Q

How often should GTN patches be changed

A

Every 24 hours

25
How soon after opening should rectal ointments be discarded?
8 weeks
26
How is isosorbide dinitrate active
Sublingually
27
How often is Dinitrate given How often is mononitrate given
BD and OD
28
What can you do to prevent tolerance with isosorbide?
Take MR isosorbide once daily tablets For BD tablets take second dose after 6-8 hours, not 12 For patches, leave off overnight ( 8-12 hours) in each 24 hours
29
Long term treatment of stable angina