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Quiz One > Hypersisitive > Flashcards

Hypersisitive Flashcards

1
Q

The types of hypersensitivity differs according to

A

Mechanism of tissue damage

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2
Q

In the 1st type of hypersensitivity the 1st exposure to an allergen lead to

A

Sensitization of must cells and basophils

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3
Q

What are preformed mediators

A

Histamine and plasma activating factor

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4
Q

What mediators are responsible for the symptoms during the late phase (type one)

A

leukotrienes and prostaglandins

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5
Q

In hypersensitivity type one, in what phase there’s recruitment of eosinophils and basophils

A

Late phase. Early phase is mainly mast cells

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6
Q

The recruitment of eosinophils and basophils causes

A

release of hydrolytic enzymes

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7
Q

True or false . Bronchial asthma is systemic type one hypersensitivity

A

F localized

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8
Q

True or false. Urticaria is localized type two hypersensitivity

A

False, type one

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9
Q

Management of anaphylactic shock
In EMERGENCY

A

Adrenaline, corticosteroids together with oxygen inhalation.

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10
Q

Antibody-dependent cell-mediated cytotoxicity (ADCC) through the action of

A

Nk

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11
Q

What type of hypersensitivity uses complement activation as a mechanism

A

Two

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12
Q

T or f
Drug reaction is an example of Type “II” hypersensitivity

A

T

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13
Q

complement activation is a mechanism in both type two and three
F or T

A

T

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14
Q

What is the effect of histamine on blood vessels

A

increase permeability

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15
Q

The main cell involved in hypersensitivity type four

A

Th1

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16
Q

In what type of hypersensitivity antibodies have no roles

A

4

17
Q

Inf-y role is

A

activates macrophages

18
Q

Th1 release………..

A

Cytokines

19
Q

T or f
continual release of Th1 cytokines leads tp accumulation of large numbers of activated macrophages

A

T

20
Q

Cause of granuloma

A

accumulation of large numbers of activated macrophages

21
Q

Whats the aim of granuloma

A

ISOLATE pathogens that resist intracellular destruction

22
Q

Granuloma is typically seen in aids patients

A

T

23
Q

In what phase of type pne hypersensitivity, there is a release of hydrolytic enzymes

A

Late phase

24
Q

The allergens of the localized form of type one hypersensitivity are widely distributed in nature
True or false

A

True

25
Q

True or false
The systemic anaphylaxis only occurs on re-exposure to an allergen to which the
individual is previously sensitized

A

T

26
Q

Diseases caused by seconed type of hypersensitivity are usually specific for a particular tissue

A

True

27
Q

What type of hypersensitivity could lead to grave diseas

A

Type two

28
Q

How to diagnois contact dermatitis

A

Skin patch test

29
Q

Example of autoimmune diseases in type four hypersensitivity

A

Insulin dopendant diabetes

Quiz One (9 decks)

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