Action Potential Flashcards

1
Q

True or false
Action potential is a change in membrane potential resulting in
Repolarization followed by
Depolarization of membrane”

A

F

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2
Q

Brief reversal of membrane potential
occurs with a total amplitude of

A

100 mv

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3
Q

What are the Two types of channels involved
in action potential in a nerve
fiber

A

Voltage (k and na)

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4
Q

True or false
Voltage potassium channels are present in smooth muscles

A

True

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5
Q

Sodium and potassium channels Gates open or close in response
to a change in

A

Membrane potential i.e. voltage

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6
Q

……is that level of membrane
potential [MP] at which action potential is
inevitable.

A

Threshold

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7
Q

T or f
At threshold potential, net
inward current becomes larger than net
outward current

A

T

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8
Q

True or false
In resting state , the membrane is more premeable to k+

A

True

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9
Q

True or false
All Voltage-Gated Na+ and K+ channels are open

A

False

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10
Q

What gate of na channel open in resting state

A

Inactivation

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11
Q

What typa channel opena qhwn depolarization happen

A

Na channel(activation gates)

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12
Q

Depolarization is due to ?

A

Opening v-g na channel

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13
Q

At the end of depeloarization what gate of na channel closes

A

Inactivation gate

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14
Q

True or false
During undershoot
Na+ tries to take mp to its equilibrium potential

A

F. Overshoot

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15
Q

True or false
At the peak of AP, membrane is closest to Na+ equilibrium
potential

A

T

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16
Q

What causes downstroke in graph?

A

Positive charges leaving cell

17
Q

Thus repolarization is caused by

A

an outward K+ current as well as stopping of Na+ influx

18
Q

True or false
Repolarization and k efflux restore the resting ionic
conditions

A

False.Repolarization and K efflux
restores the resting electrical
conditions of the neuron only

19
Q

Ionic redistribution back to
resting condition is restored by
the

A

sodium-potassium pump

20
Q

True or false
During Resting state more K+ leaking out, less Na+ leaking in

21
Q

Graded potential are produced by

A

Soma and dendrites

22
Q

Graded potentials are produced in dendrites and soma due to

A

Opening of ligand gated channels

23
Q

Action potential fires up at which region

A

in the region of initial segment rich in V-G Na+

24
Q

The transmission of a depolarization process along a nerve fiber is called

A

Nerve impulse

25
When does voltage gated Ca++ channels open
When AP reaches axon terminal
26
Speed of propagation depends on
Myelination Diameter كلهم علاقتهم طردية
27
What type of impulse conducting is faster
Saltatory
28
"The time period during which another normal AP can not be generated, no matter how strong is the stimulus. " This is a definition of?
Shows refractiry period
29
Whats this Diffention Time from the opening of the Na+ activation gates (threshold) followed by closure of inactivation gates that enter a closed, inactive state.
Absolute refractory period
30
True or false In relative refactory period k+ gates are open and repolarization is occuring
True
31
Why in the relative refactory pitiontal the supra-threshold stimuli can open Na channels to cause AP
Cause The threshold level is elevated
32
the magnitude of ap is dependent upon
1-serum Na+ level Refactory period
33
True or false The action potential amplitude depends on strength
F. It follows all or none law
34
I cardiac and smooth muscles what ions enter the cell to produce depolarization
calcium
35
Affect of hyperkalemia on membrane
depolarization c
36
Hypokalemia affect on membrane
Hyperpolarizing
37
What happens when ca binds to na
stabilize the electrical state of Na+ channels.
38
Whats the cause behind muscle tetany
Hypocakcemia
39
At the peak of AP, membrane is closest to ...... equilibrium potential
Na