Action Potential Flashcards

1
Q

True or false
Action potential is a change in membrane potential resulting in
Repolarization followed by
Depolarization of membrane”

A

F

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2
Q

Brief reversal of membrane potential
occurs with a total amplitude of

A

100 mv

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3
Q

What are the Two types of channels involved
in action potential in a nerve
fiber

A

Voltage (k and na)

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4
Q

True or false
Voltage potassium channels are present in smooth muscles

A

True

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5
Q

Sodium and potassium channels Gates open or close in response
to a change in

A

Membrane potential i.e. voltage

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6
Q

……is that level of membrane
potential [MP] at which action potential is
inevitable.

A

Threshold

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7
Q

T or f
At threshold potential, net
inward current becomes larger than net
outward current

A

T

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8
Q

True or false
In resting state , the membrane is more premeable to k+

A

True

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9
Q

True or false
All Voltage-Gated Na+ and K+ channels are open

A

False

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10
Q

What gate of na channel open in resting state

A

Inactivation

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11
Q

What typa channel opena qhwn depolarization happen

A

Na channel(activation gates)

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12
Q

Depolarization is due to ?

A

Opening v-g na channel

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13
Q

At the end of depeloarization what gate of na channel closes

A

Inactivation gate

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14
Q

True or false
During undershoot
Na+ tries to take mp to its equilibrium potential

A

F. Overshoot

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15
Q

True or false
At the peak of AP, membrane is closest to Na+ equilibrium
potential

A

T

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16
Q

What causes downstroke in graph?

A

Positive charges leaving cell

17
Q

Thus repolarization is caused by

A

an outward K+ current as well as stopping of Na+ influx

18
Q

True or false
Repolarization and k efflux restore the resting ionic
conditions

A

False.Repolarization and K efflux
restores the resting electrical
conditions of the neuron only

19
Q

Ionic redistribution back to
resting condition is restored by
the

A

sodium-potassium pump

20
Q

True or false
During Resting state more K+ leaking out, less Na+ leaking in

A

True

21
Q

Graded potential are produced by

A

Soma and dendrites

22
Q

Graded potentials are produced in dendrites and soma due to

A

Opening of ligand gated channels

23
Q

Action potential fires up at which region

A

in the region of initial segment rich in V-G Na+

24
Q

The transmission of a depolarization process along a nerve fiber is called

A

Nerve impulse

25
Q

When does voltage gated Ca++ channels open

A

When AP reaches axon terminal

26
Q

Speed of propagation depends on

A

Myelination
Diameter
كلهم علاقتهم طردية

27
Q

What type of impulse conducting is faster

A

Saltatory

28
Q

“The time period during which another normal AP can
not be generated, no matter how strong is the stimulus.

This is a definition of?

A

Shows refractiry period

29
Q

Whats this Diffention
Time from the opening of the Na+ activation gates (threshold) followed by closure of inactivation gates that enter a
closed, inactive state.

A

Absolute refractory period

30
Q

True or false
In relative refactory period k+ gates are open and repolarization is occuring

A

True

31
Q

Why in the relative refactory pitiontal the supra-threshold stimuli can open Na channels to cause AP

A

Cause The threshold level is elevated

32
Q

the magnitude of ap is dependent upon

A

1-serum Na+ level
Refactory period

33
Q

True or false
The action potential amplitude depends on strength

A

F. It follows all or none law

34
Q

I cardiac and smooth muscles what ions enter the cell to produce depolarization

A

calcium

35
Q

Affect of hyperkalemia on membrane

A

depolarization c

36
Q

Hypokalemia affect on membrane

A

Hyperpolarizing

37
Q

What happens when ca binds to na

A

stabilize the
electrical state of Na+ channels.

38
Q

Whats the cause behind muscle tetany

A

Hypocakcemia

39
Q

At the peak of AP, membrane is closest to …… equilibrium
potential

A

Na