Embryo Vertebrae Flashcards

1
Q

The intraembryonic mesdoderm is Located between Ectoderm & Endoderm EXCEPT in

A

in the central
axis of embryo where NOTOCHORD is found.

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2
Q

The intervertebral disc is formed by

A

Mesenchymal cells

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3
Q

What forms the nucleus pulposus

A

The notocord

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4
Q

In what week chondrification centers appear in each
mesenchymal vertebra.

A

6

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5
Q

In what week does the chondrification centers fuse with each other

A

8

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6
Q

Primary ossification centers appear during what week

A

8

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7
Q

As the vertebrae form, two primary curves of the spine are established:

A

Thoracic and sacral

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8
Q

Later on in postnatal life, two secondary SECONDARY
curves are established:

A

Lumbar and cervical

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9
Q

What gene is responsible
for the proper orientation of the vertebrae in the
cranio-caudal direction

A

Hox

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10
Q

What gene is found to play an
essential role in anterior-posterior development,
the ventral neural tube and somite patterning.

A

Shh

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11
Q

Whats the name of the conginatal anomaly when two successive vertebrae fuse asymmetrically or have half a vertebra missing.

A

scoliosis

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12
Q

what anomaly is it when the cervical vertebrae are fused
causing reduced mobility
and a short neck.

A

Klippel-feil syndrome

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13
Q

what anomalies are related to vertebral bodies

A

S coliosis
Klippel–Feil Syndrome

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14
Q

T or f
Spina bifida is a Congenital Anomaly related to Vertebral Arch

A

T

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15
Q

Mesoderm differentiates into

A

Paraxial mesoderm
Intermidiate mesoderm
Lateral mesoderm

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16
Q

Paraxial mesoderm differntiate into

A

Somites

17
Q

True or false
Somites develop in a anteroposterior direction

A

F, craniocaudal

18
Q

What part of the somite is scleotomes

A

Ventromedial

19
Q

In what week does sclerotome cells migrate
around the spinal cord and
notochord to merge with
cells from the opposing
somite

A

4

20
Q

True or false
The body of each is formed by resegmentation
(combination of the caudal half
of the somite above and the
cranial half of the somite below. )

A

T

21
Q

What bridges the intervertebral disc

A

Myotomea

22
Q

What makes the nucleus pulposus

A

Notochord

23
Q

In what week dows the chondrification cetenr appear

A

6

24
Q

Chondrifiction centers fuse at what week

A

8

25
Q

ossification centers apear during what week

A

8

26
Q

T or f
Sacral curvature forms when the
child learns to walk.

A

F lumbar