Hypersensitivity Flashcards
1
Q
peanut allergy
A
become systemic because immune cells in the stomach release histamine, C3a and C5a into the vasculature
2
Q
devics disease- neuromyelitis optica
A
lesions in spinal cord and severe optic neuritis
antibody against aquaporin 4, fixes complement, causes death to astrocyte and release of toxins kills oligodendrocytes
astrocyte damage is primary pathology
3
Q
polyarteritis nodosa
A
type 3 rxn to Heb B
systemic vasculitis w/ necrotizing lesions in medium and small muscular arteries, aneurysm, ischemia, thrombosis, and infarction
affects multiple systems and has many manifestations
4
Q
fibrosing schistosomiasis
A
parasites live in mesenteric veins. lay eggs that ilicit eosinophilic, granulatomas rxn in liver, bowel, and bladder
IL4, 5, 13 associated
