Hypersensitivity 1 (RVSP) Flashcards
Exaggerated response to a harmless antigen that results to an injury in the tissue, disease or even death
Hypersensitivity
Heightened state of immune responsiveness
Hypersensitivity
AKA Type 1
Atopic
Immune system involved in Type 1
Humoral (IgE)
Effectors in Type 1
Mast cells Eosinophils
Effects of Type 1
Inflammation (anaphylaxis)
Onset of type 1
Seconds
AKA Type 2
Cytotoxic
Immune system involed in type 2
Humoral (IgG & IgM)/Complement
Effectors in Type 2
Macrophages Complement
Effects of Type 2
Cell destruction (hemolysis)
Onset of Type 2
hours
AKA Type 3
Immune Complex
Immune system involved in Type 3
Humoral (IgG & IgM)/Complement Sabi sa Stevens na IgG and IgM :)
Effectors in Type 3
Granulocytes (T cell)
Effects of Type 3
Inflammation
Onset of Type 3
Hours
AKA Type 4
Delayed Type
Immune system involed in Type 4
Cell-mediated
Effector in Type 4
Macrophage
Effects of Type 4
Inflammation
Onset of Type 4
Days
Classic Allergy is known as
Type 1
Type 1 Hypersensitivity is mediated by ____ attached to ________
IgE, Mast cells
Non-parasite antigens that can stimulate a Type 1 Hypersensitivity response
Allergens
Antibody that allergens bind to
IgE
Effect of allergens on IgE
Triggers degranulation of chemical mediators
Enumerate common allergens associated with type 1 hypersensitivity
MW of allergens
15000-45000 MW
True/False. Allergens are proteins
True
Dosage of allergen to ellicit type 1 hypersensitivity
Low dose
