Hyperlipidemia 5

Question 1

What are two genetic lipid disorders?

Answer 1

1. Familial hypercholesterolemia
2. Familial hyperchylomicronemia

Question 2

Which genetic disorder?

–LDL receptors absent or dysfunctional

–Homozygotes: LDL 8x normal

–Heterozygotes: LDL 2x normal

Answer 2

Familial hypercholesterolemia

Question 3

Which genetic disorder?

Lipoprotein lipase abnormality

• Enzyme that allows peripheral tissue to take up TG from chylomicrons and VLDL
• Severe hypertriglyceridemia

Answer 3

Familial hyperchylomicronemia

Question 4

What is the following describing?

–Transported through blood within lipoproteins

–Transported into skeletal muscle and adipose tissue to use as energy

Answer 4

Triglycerides

Question 5

Elevated triglycerides have been seen with decreased HDL–> Is this an independent risk factor for CVD?

Answer 5

It is UNKNOWN if this is an independent risk factor

Question 6

Which syndrome has 3 of the following:

1. Central obesity
2. High BP
3. High triglycerides
4. Low HDL-cholesterol
5. Insulin resistance

Answer 6

Metabolic syndrome

Question 7

200-499 mg/dL is:

A. Severe hypertriglyceridemia

B. Mild hypertriglyceridemia

C. Moderate hypertriglyceridemia

Answer 7

B. Mild hypertriglyceridemia

Question 8

>500 mg/dL is:

A. Severe hypertriglyceridemia

B. Mild hypertriglyceridemia

C. Moderate hypertriglyceridemia

Answer 8

C. Moderate hypertriglyceridemia

Question 9

>1000 mg/dL is:

A. Severe hypertriglyceridemia

B. Mild hypertriglyceridemia

C. Moderate hypertriglyceridemia

Answer 9

A. Severe hypertriglyceridemia

Question 10

Mild, moderate or severe hypertriglyceridemia?

>1000 mg/dL

• Milky white serum

Acute pancreatitis

Answer 10

Severe hypertriglyceridemia

Question 11

What healthy lifestyle behaviors should be recommended in ALL patients?

Answer 11

1. Low saturated fat, low trans fat
2. Low sodium
3. Regular aerobic exercise
4. Avoid tobacco products