Hydration and Exercise Flashcards
What are the typical volumes of different fluids in the body for a 70kg individual? (armstrong 2007)
28 L Intercellular fluid
11 L interstitial fluid
3 L Plasma
What are the characteristics of intracellular dehydration?
- Fluid loss is hypo-osmotic to plasma
- Loss of water is greater than loss of osmolytes = increase in plasma osmolality
- An osmotic gradiant is created and water loss is shared between ICF and ECF
- Associated with sweat loss due to exercise-heat stress
What are the characteristics of extracellular dehydration?
- Fluid loss is iso-osmotic with plasma
- Loss of water and osmolytes occur in equal proportions = normal blood chemistry
- The osmotic gradient to pull fluid from the larger internal reservoir is absent
- Associated with fluid losses induced by diuretics, diarrhea and cold and altitude
What volume of fluid loss leads to 2% dehydration in a typical 70kg individual?
1.4L
What does AVP stand for and what’s another name for it?
Arginine Vasopressin; A.K.A Antidiuretic Hormone or ADH
What roles does AVP have in dehydration? (explain step by step)
- Cellular shrinkage due to dehydration
- Sensed by osmoreceptors in brain
- Increase neural firing
- AVP secreted by hypothalamous
- Concentrates urine by increasing water absorption
What are measures of both ICD and ECD?
Bioimpedence, BIVA, symptoms and BUN/Cr in the blood
What are the primary measures of ICD?
Blood plasma osmolality, Urine osmolality, and Urine specific gravity
What is the range of euhydrated blood plasma osmolality?
280-290 mOsmol/kg
What is euhydrated urine osmolality?
less than 700 mOsmol/kg
What is dehydrated urine osmolality?
more than 900 mOsmol/kg
What is the euhydrated Urine specific gravity
less than 1.020 g/mL
When is the best time to measure urine osmolality?
First morning void
Which of plasma and urine osmolality is quicker to respond to de/re-hydration?
plasma is quicker. urine has a delay
What is the relationship between stroke volume/HR and fluid loss? (montain and coyle 1992)
SV: Proportional negative relationship. As more fluid is lost, stroke volume decreases
HR: Proportional positive relationship