HWE: Selection - 7 Flashcards
Define selection
individuals with certain phenotypes have higher survival and/or reproduction
(phenotypes must be heritable)
What are the problems with selection (3)
environmental influences, multigenic traits, and continuous traits (vs. discrete)
What happens if there is equal selection on homozygotes
if equal selection pressure starting with equal frequencies, then no changes will occur, but if start with any frequencies that are not equal, then changes will occur.
the genotype frequencies will be affected (heterozygotes will increase), but NOT allele frequencies
How fast are the changes in frequencies if there are big vs small differences in selection
small differences in selection will cause big changes over time
large differences will cause changes quickly
Define absolute vs. relative fitness
absolute = number of offspring of an organism of a specific genotype
relative = the fitness of a genotype relative to the most (the fittest) genotype
the rate of change depends on _____, not ____ fitness
relative
absolute
What defines the selection coefficient
relative fitness (w)
What does a positive and negative selection coefficient mean
positive = selected against
negative = selected for
The best genotype has a fitness of ____
1
How do you calculate relative fitness
dividing each genotypes survival and/or reproduction by the highest survival and/or reproduction rate
How do you calculate the selection coefficient (s)
relative fitness (w) - 1 = s
What occurs after selection depending on if a lethal allele is recessive vs. dominant
if recessive = never fully goes away because it is still present and hidden in heterozygotes
if dominant = it will disappear almost instantly because there is no place for it to hide
What are the percentages that determine if an allele is rare or common
rare allele frequency = <5%
common allele frequency >95%
How does selection for a rare recessive, common recessive, rare dominant and common dominant influence the allele frequency over time
rare recessive = evolution by selection is slow because they are present in heterozygous individuals
dominant rare (and common recessive) = evolution by selection is fast
Does strong selection always result in fixation
No, commonly something else occurs too such as, heterozygous superiority (heterozygous individual has greater fitness than either homozygous) which also prevents the loss of the lethal allele (because it can still hide) or can occur will heterozygote inferiority