Human Reproduction Flashcards

1
Q

Perimeter IgM

A

Thein exxternal peritoneal layer

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2
Q

Myometrium

A

Thigh smooth msucle layer

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3
Q

Endometrium

A

Thin internal layer

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4
Q

Mittelschmerz

A

Abdominal pain accompanying ovulation
It is a secondary sign of ovulation however there are better primary indicators such as body temp, fertile cervical mucus, and change int he cervical position

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5
Q

Some women do not ovulate (anovulation) bc of an inadequate release of ___

A

Gonadotropins

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6
Q

In some women ovulation can be induced by administration of ____ or an ovulation agent, resulting in maturation of several ovarian follicles and multiple ovulation

A

Gonadotropins

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7
Q

The incidence of what can increase when ovulation is induced

A

Multiple pregnancies

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8
Q

In anovulatory cycles the proliferation of the endometrium develops as usual, but ___ does not occur and no __ __forms

A

Ovulation corpus luteum

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9
Q

In anovulatory cycles, the endometrium does not progress to the ___ __. It remains in what phase until mensruation begins

A

Leutal

Proliferation

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10
Q

Estrogen oral contraceptives with or without progesterone suppress ovulation how

A

Acting on the hypothalamus and pituitary gland inhibiting secretion of gonadotropin releasing hormone, follicle stimulating hormone and lutenizing hormone

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11
Q

Sperm accounts for what percent of the volume semen

A

Less than 5

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12
Q

What is the remainder of ejaculate

A

60% secretions from the seminal glands
30% prostate
5% bulbourethral glands

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13
Q

How many sperm is in ejaculate

A

100 million Spears per mililiter of semen

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14
Q

What level of sperm is considered infertible

A

20-50 million

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15
Q

What level of sperm is steril

A

10 million, esipcially when it contains immobile and abnormal sperm

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16
Q

What may cause male infertility

A

Endocrine disorders, abnormal spermatogenesis, reduced levels of seminal plasma proteins, or obstruction of a genital duct

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17
Q

Male infertility is found in what percent of involuntarily childless couples

A

30-50

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18
Q

Vasectomy

A

Excision of a segment of the ductus deferens

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19
Q

How long after vasectomy are there no sperm in the ejaculate. Has the volume changed?

A

2-3 weeks

No

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20
Q

IVF

A

In vitro fertilization of oocytes and transfer of either the dividing zygotes or a blastocyst into the uterus

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21
Q

The incidence of what is higher with IVF

A

Multiple pregnancies and spontaneous abortion

22
Q

How can we tell the sex of a baby very early

A

Bastomere taken from a six to eight cell zygote and analyze for amplification of Y chromosome

23
Q

Why determine the sex at 6 to eight cell zygote stage 1st week

A

In case of x linked disorder want female

24
Q

Can the polar body be tested for genetic disorders during 1st week

A

When mother is carrier

25
Why may early implantation of blastocyst fail
Inadequate production of progesterone and estrogen by the corpus luteum
26
How does patient present with Spontaneous abortion
Last menstrual period was delayed by several days whose last flow was profuse
27
Overall early spontaneous abortion rate is _%
45
28
Early spontaneous abortion is usually due to the presence of __ __
Chromosomal abnormalities
29
Blastocysts sometimes Implant outside the uterus.
Ectopic pregnancy
30
Where are most ectopic preg
Uterine tubes in the ampulla and isthmus
31
Frequency of ectopic tubal pregnancy
1/200
32
Symptoms of tubal pregnancy
Abdominal pain, abnormal bleeding, and irritation of the pelvic peritoneum
33
Causes of ectopic pregnancy
Factors that delay or prevent transport of the cleaving zygote to the uterus
34
Ectopic tubal pregnancies usually result in __ of the uterin tube and hemorrhage into the peritoneal cavity during the first 8 weeks followed by death of embryo
Rupture
35
What is the morning after pill
Large dose of estrogen for several dats after unprotected sexual intercourse
36
What does the morning after pill prevent
Usually doesn’t prevent fertilization, it prevents implantation of the blastocyst The endometrium progresses to the lateral phase of the menstrual cycle as the zygote forms, undergoes cleavage and enters the uterus. But a large amount of estrogen disturbs the normal balance between estrogen and progesterone that is necessary to prepar the endometrium for implantation
37
IUD
Interferes with implantation by causing a local inflammatory reaction
38
Som IUD contain slow release progesterone, which interferes with what
Development of the endometrium so that implantation does not usually occur
39
Copper based IUD
Inhibit migration of sperm into the tube
40
Levonnorgestrel based IUD
Alter the quality of the cervical mucus and endometrial development
41
Sacrococcygeal teratomas
Remnants of the primitive streak may persist and give rise to a large tumor
42
Why can a sacrococcygeal teratomas contain tissues derived from all three germ layers in incomplete stages of differentiation
Bc it is derived from pluripotent primitive streak cells
43
What is the most common tumor in newborn infants
Sacrococcygeal teratomas | 1/27000
44
Prognosis of sacrococcygeal teratomas
Good usually just removed
45
Disturbance of neurulation may result in what
Severe abnormalities of the brain and spinal cord
46
Meroencephaly(anencephaly)
Partial absence of the brain
47
Wh get. NTD
Neuroectoderm | Failure of neural folds to fuse and form the neural tube
48
Spina bidifa cystica
NT fails to fuse in lumbar region
49
Hydatidiform moles
Sometimes the embryo dies and the chorionic villi do not complete their development ; they do not become vascularized to form tertiary villi
50
Hydatidiform moles exhibit variable degrees of __ proliferation and produce excesssive amounts of hCG
Trophoblastic
51
In _% of cases hydatidiform moles develop into malignant trophoblastic lesions called ______
3-5 | Choriocarcinomas
52
Choriocarcinoma
Metasticise by blood to various sites such as lungs, vagina, liver, bone intestine, and brain