Human Inmunodeficiency Virus Flashcards

1
Q

what class of virus is HIV

A

retrovirus

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2
Q

what cells in the body does HIV attack

A

cells of the immune system; lymphocytes and macrophages

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3
Q

what does HIV do to the immune system

A

erodes the immune system over years and causes immunodeficiency and susceptibility

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4
Q

aetiology/ causes (MODES OF TRANSMISSION)

A

HIV can be transmitted via blood, blood products, sexual fluids, other fluids containing blood, and breast milk. Most individuals are infected with HIV through sexual contact, before birth or during delivery, during breastfeeding, or when sharing contaminated needles and syringes (intravenous drug users)

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5
Q

how can you determine the progression of the disease

A

CD4 T-cell count

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6
Q

what are the three phases of HIV

A

seroconversion, Early/asymptomatic, AIDS

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7
Q

summarise seroconversion stage

A

fever, night sweats, fatigue, malaise, oral thrush, ulcers, sore throat, headache

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8
Q

summarise the early/ asymptomatic stage

A

patient is apparently well, might have persistent lymphadenopathy, minor symptoms such as rash, oral thrush and weight loss

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9
Q

summarise the AIDS stage (late stage)

A

syndrome of secondary infections as a result of immunodeficiency

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10
Q

some signs and symptoms (neurological)

A

polyneuropathy, dementia

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11
Q

some signs and symptoms (pulmonary)

A

pneumonitis

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12
Q

some signs and symptoms (gastro)

A

anorexia, wasting, diarrhoea

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13
Q

some signs and symptoms (haematology)

A

anaemia, thrombocytopenia

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14
Q

some signs and symptoms (cardiac)

A

cardiomyopathy, myocarditis

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15
Q

some signs and symptoms (eyes)

A

cotton wool spots

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16
Q

secondary infections

A

bacterial, viral, fungal, protozoal, tumours (Kaposi sarcoma)

17
Q

investigations (testing for HIV itself)

A

ELISA, PCR, viral load, CD4 T cell count

18
Q

what other investigations may be done for someone that is HIV positive

A

CXR etc, to check for secondary damage

19
Q

prevention of HIV

A

PrEp - pre exposure prophylaxis

Condoms

20
Q

management of HIV

A

start the patient on antiretroviral therapy

PLUS
supportive care (counselling)