Human Immunodeficiency Virus (HIV) Flashcards
What populations are disproportionately affected for HIV?
(a) Sex workers (12x higher infection rate than general population).
(b) IV drug users, prisoners.
(c) Men who have sex with men, transgender people.
Average time from infection to the development of symptoms is ______, although incubation periods as long as _____ months have been observed
2-4 weeks, ten months
HIV can advance to AIDs within how long?
10 years or longer
The acute phase of HIV infection (symptomatic) is called what?
Acute
Retroviral Syndrome (ARS)
ARS can present similarly to what diseases?
infectious mononucleosis or influenza
What issue?
Commonly includes fever, maculopapular rash, arthralgia, myalgia, malaise, lymphadenopathy, oral ulcers, pharyngitis, and weight loss
The presence of fever and rash have the best positive predictive value
Acute Retroviral Syndrome (ARS)
HIV – Laboratory Testing
-Screening test OraQuick ADVANCE Rapid HIV-1/2 Antibody Test
-Confirmatory testing performed via 4th Gen HIV immunoassay
HIV – DDx
(1) Mononucleosis due to Epstein-Barr virus (EBV)
(2) Cytomegalovirus (CMV)
(3) Influenza
(4) Positive Oraquick:
What is the Guidance for HIV (PrEP) for Persons at High Risk.
DHA IPM 18-020
nPEP (Nonoccupational Post-exposure Prophylaxis)
(a) When is this relevant?
1) Sexual Assault
2) Unprotected sexual contact with high-risk contact
PEP (Occupational Post-Exposure Prophylaxis)
(a) When is this relevant?
1) Needlesticks
2) Healthcare related exposure to high-risk substances
When to contact MedAdvice and/or routine MedEvac:
(a) Positive screening with Oraquick rapid HIV test.
(b) Positive confirmatory testing utilizing 4th generation HIV
Ab/Ag.
(c) High clinical suspicion of ARS.
(d) Needle Stick/bloodborne exposure to high-risk individual.
______________ medications have radically altered HIV infection
Antiretroviral
What is the instruction for HIV in Military Service Members
DoDI 6485.01
Clinical evaluations required by military infectious disease
physicians at least every ______ after diagnosis
6 to 12 months