Human Genetics - Lecture 14

Question 1

Why is identifying disease genes matter?

Answer 1

○ Genetic testing for disease prevention
○ New treatments
○ Insight into common diseases

Question 2

What DNA markers are used for genetic mapping?

Answer 2

○ Short tandem repeats (STRs)
○ Single nucleotide polymorphisms (SNPs)

Question 3

What are short tandem repeats?

Answer 3

○ Tandem repeats of a short sequence
○ Usually 2-4 nucleotides
○ Usually in non-coding sequences
○ Longer repeats (>10 nucleotides) are known as minisatellite repeats
○ Used in forensic analysis

Question 4

How does DNA profiling help law enforcement?

Answer 4

○ Unique DNA
○ Crime scene evidence
○ Database comparison
○ Family links

Question 5

What is single nucleotide polymorphisms (SNPs)?

Answer 5

○ A single nucleotide difference between individuals
○ Most are in non-coding DNA
○ Most common type of polymorphism in human genome