HUBS 191 Lecture 5 Flashcards

1
Q

how does bone growth start

A

with a cartilage model which forms 6 weeks after fertilisation and acts as a blueprint for the structure of bones

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2
Q

what is the process of turning cartilage into bone called

A

endochondral ossification

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3
Q

where are the primary and secondary ossification centres

A

primary - diaphysis
secondary - epiphyses

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4
Q

what is the cartilage between the diaphysis and epiphyses that allows for growth of the bone (in length) called

A

the growth (epiphyseal) plates

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5
Q

what is appositional growth

A

growth in the width of bones in order to support our body weight as we get older

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6
Q

what is a joint

A

a combination of soft tissues that hold together bones (this involves the ends of bones).

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7
Q

what are the three types of cartilage

A

elastic (not important for hubs)
hyaline/articular cartilage
fibrocartilage

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8
Q

what tissue composes ligaments, tendons and joint capsules

A

DFCT - dense fibrous connective tissue

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9
Q

what do chondrocytes do

A

make cartilage in lacunae

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10
Q

what are the positives and negatives of cartilage being avascular

A

if force is applied it has no effect on the cartilage because there is no blood flow to stop

its very hard to get nutrients in to the cells that need them

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11
Q

how does the cartilage diffuse nutrients into the chondrocytes

A

the cartilage joint loads which means it pushes fluid (containing nutrients) into the tissue and hopes that the cells get the nutrients they need

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12
Q

what makes hyaline cartilage good at resisting compression

A

it has a high water concentration in the matrix

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13
Q

what is the function of hyaline cartilage

A

to resist compression. it moulds to the bone surface where the bones articulate and provides a smooth frictionless surface for movement

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14
Q

what is the function of fibrocartilage

A

to resist compression and tension (its a good shock absorber, can distribute weight force over a wider area and can be used to deepen articulations)

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15
Q

what is fibrocartilage composed of

A

lots of collagen fibres in bundles that are aligned with the stresses/tensions that the cartilage will experience. there are also chondrocytes in lacunae. the ECM also contains some water

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16
Q

what is DFCT composed of

A

fibroblasts (cells that make fibre, usually collagen), collagen fibres and some elastin fibres (not always)

17
Q

What is the function of DFCT

A

to resist tension - there is no room in the ECM for water so it can’t resist compression very well

18
Q

why is DFCT slow to heal

A

because it is so tightly packed and has very little vascularity which means it takes a long time for nutrients to get through

19
Q

what is the function of ligaments

A

to connect bone to bone

20
Q

what are ligaments composed of

A

collagen and elastin (which allow them to resist tension)

21
Q

what is the function of tendons

A

to connect bone to muscle

22
Q

how is composition of tendons different to that of ligaments

A

tendons contain less elastin than ligaments (because we want them to be more rigid)

23
Q

what is bony congruence

A

the sum of surfaces that form an articulation

24
Q

what does high bony congruence mean

A

the joint is stable

25
Q

what does low bony congruence mean

A

the joint isn’t very stable and might need more soft tissue for support

26
Q

what are the three joint classifications

A

fibrous - least amount of movement (skull sutures)
cartilaginous
synovial - most amount of movement (most limb joints)

27
Q

what are fibrous joints composed of

A

DFCT - that functions to restrict movement and provide stability

28
Q

what are cartilaginous joints composed of

A

fibrocartilage - structure varies but they all function to allow some movement