HTN, preconception topics, OB emergencies Flashcards
Three biggest risk factors for pre-eclampsia
Chronic renal disease (RR 20), cHTN (RR 10), APS (RR 10)
Anomalies possibly associated with cHTN
Hypospadias, esophageal atresia, cardiac septal defects
What types of drugs are dinoprostone and misoprostol?
PGE2 and PGE1
Risks of hygroscopic dilators
Endometritis (60% vs 11%) Neonatal sepsis (12% vs 0%)
Half life of pitocin
3-10min
Inheritance pattern of CF
Autosomal recessive
Inheritance pattern of SMA
Autosomal recessive
Highest risk of being CF carrier by ethnicity
Caucasian (1/25), Ashkenazi Jewish (1/24), Hispanic (1/58), African American (1/64), Asian American (1/94)
When to screen for fragile X
Family history of mental retardation, premature ovarian failure, elevated FSH prior to age 40
Normal adult hemoglobin fractions
A1 >95% A2 <3.5% F <2% S 0% (suspect beta-thal if dec A1 and inc A2)
ACOG recommends screening for which conditions if Ashkenazi Jewish? (4)
CF, Tay-Sachs, Canavan, familial dysautonomia
Recommended folic acid supplement for no history and for history of NTD
400 mcg / day or 4 mg / day
typical prenatal vitamin has 1 mg
Dose / timing of methergine
0.2 mg IM q2-4 hrs
Dose / timing of hemabate
0.25 mg IM q15-90min (max 8 doses)
Incidence of accreta by # of prior C/S and previa
0 = 3% 1 = 11% 2 = 40% 3 = 61% 4 = 67% >4 = 67% (and 4.7% even without a previa)
Risk for recurrent accreta if no hysterectomy performed
20% risk
Volume / contents of 1 u pRBCs
300 mL (250 mL RBCs and 50 mL plasma)
Volume / contents of 1 u plt
50 mL (typically 6-10 u transfused together) -> increase plt by 7500/mm3
Volume / contents of 1 u FFP
250 mL (plasma = fibrinogen, antithrombin, factors V, XI, and XII)
Volume / contents of 1 u cryo
40 mL (fibrinogen, factor VII, vWF, factor XIII) -> increase fibrinogen by 5-10 mg/dL per unit
Local anesthesia causing worst cardiac toxicity
Bupivicaine due to long duration of action
