HSP Flashcards

1
Q

Urgent Findings that need intervention

A
  1. AMS - significant change from baseline mental status (lack of perfusion to brain, not protecting airway)
  2. Respiratory Distress/Depression - tachypnea, grunting, slow shallow breathing –> all suggests compromise of oxygenation and ventilation
  3. Mottled Skin/Cyanosis - inadequate tissue perfusion or oxygenation –> NEED TO FIX
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2
Q

Mechanism of petechiae and purpura

A
Trauma
Platelet deficiency/dysfunction
Coagulation abnormalities
Vascular fragility (vasculitis)
Combo
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3
Q

Get the patient’s perspective

A

What do you think is going on?
What concerns you most?
What do you think happened?

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4
Q

DDx for bruising and leg pain

A
Coag disorder
Henoch-schonlein purpura
idiopathic thrombocytopenic purpura
leukemia
viral infection
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5
Q

Coagulation disorder

A

may present with petechiae or small bruising, hemarthrosis, minor trauma, family history

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6
Q

Henoch-Schonlein Purpura presentation

A

often as otherwise healthy child with leg bruises and pain walking
50% of cases have URI preceding bruising

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7
Q

ITP

A

asymptomatic petechiae –> URI preceding

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8
Q

Leukemia

A

consititutional symptoms of fever, malaise, weight loss

- bone pain from infiltration of bone marrow with leukemic cells and bruising from thrombocytopenia

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9
Q

Viral Infection

A

enterovirus can cause petechiae rash and sometimes pain with walking

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10
Q

Examining lymph nodes

A
Size --> >2 cm = concern
Location
Tenderness
Texture
Mobility - hard and non-mobile = concern
Distribution --> diffuse = concern
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11
Q

Hepatomegaly

A

although palpating liver can be normal –> if you feel it, you need to investigate it further

  • can be from inflammation, infiltration, accumulation of storage material, congestion, or obstruction
  • can percuss to hear difference or feel by palpation
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12
Q

Causes of arthralgia or arthritis in kids

A

Trauma, septic arthritis, transient synovitis, reactive arthritis
Lyme disease, rheumatic fever, lupus, HSP

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13
Q

DDx for rash and leg pain

A
  1. HSP - rash unique for tendency for lower extremities and buttocks (periarticular vasculitis) –> no splenomegaly
  2. ITP - no splenomegaly
  3. Leukemia - bone pain, splenomegaly, lymphadenopathy
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14
Q

Splenomegaly

A

Infection - EBV, CMV, Sepsis, endocarditis
Hemolysis - sickle cell
Malignancy - leukemia, lymphoma
Lupus, venous congestion, CHF

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15
Q

Examining the spleen

A

lie supine or in lateral position –> palpate anteriorly and posteriorly

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16
Q

Labs for HSP

A
  1. CBC with smear - need platelet count for ITP vs HSP
  2. BUN and Cr - determine extent of renal involvement
  3. UA - hematuria/proteinuria
17
Q

HSP

A

self-limited IgA mediated small vasculitis that involves skin, GI, renal, joints
- most commonly diagnosed vasculitis in kids
HALLMARK = non-thrombocytopenic purpura
1/3 have renal involvement
- early steroids MAY prevent GI and renal involvement

18
Q

ITP diagnosis

A

binding of antiplatelet antibody to platelet surface –> removal and destruction of platelets in spleen and liver
*smear shows immature giant platelets cells

19
Q

HSP prognosis

A

symptoms usually last a month and self-resolve without treatment

  • resample urine to monitor kidney function and BP
  • re-evaluate if things get worse
20
Q

Intussusception

A

telescoping of proximal bowel into distal bowel –> bowel compression and ischemia
- most common cause of bowel obstruction in kids 6 months - 6 years
- paroxysmal abdominal pain, currant jelly stools, sausage felt in abdomen
Tx = air or barium enema, US

21
Q

Complications of HSP

A
  1. GI Bleeding - 50% have this, from same inflammation that caused vasculitis, stool guaiac test to confirm –> short course of steroids
  2. Kidney - 1/3 of kids have kidney problems –> hematuria and self-resolving
22
Q

Recurrence of HSP

A

30% - weeks to months after 1st episode

- same symptoms