how mutation happens Flashcards

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1
Q

spontaneous mutations

A

occur in the absence of a chemical or physical mutagenic agent

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2
Q

spontaneous mutation includes

A

ACTG incorporation mistakes during DNA replication

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3
Q

spontaneous mutation frequency

A

1 in 10 replicated base pairs or 1 in 10 replicated genes

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4
Q

induced mutations

A

occur when a mutagenic agent is present

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5
Q

induced mutations includes

A

incorporation of base analogs (e.g. bromo-uracil)

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6
Q

induced mutation frequency

A

far higher than spontaneous mutation rates but is dependent upon concentration of mutagen

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