Horner's Syndrome

Question 1

Causes

Answer 1

Pancoast tumour

Carotid artery dissection

Question 2

Investigations - explain cocaine eye tests

Answer 2

Cocaine blocks NA reuptake
Therefore normally this would cause dilation
However in Horner’s syndrome, there’s no neurotrasnmitter

Question 3

Apraclonidine

Answer 3

Weak alpha 1 agonist

Question 4

Apraclonidine

Answer 4

Weak alpha 1 agonist therefore normally it’s too weak to compete with noradrenaline and cause dilation of pupil, but it Horner’s there’s no NA therefore it does cause pupil dilation