Aspirin OD

Question 1

Symptoms of salicylate poisoning. What might develop in severe cases intially?

Answer 1

Nausea, vomiting, tinnitus and headache

If severe: hyperventilation and a secondary respiratory alkalosis

Question 2

Severe OD signs on ABG

Answer 2

Progresses to metabolic acidosis and hypokalaemia

Question 3

Signs of severe OD

Answer 3

Confusion, coma, seizures, hypoglycaemia

Question 4

Mx if recent / severe

Answer 4

Recent OD - activated charcoal
Severe OD - IV bicarbonates

to maintain blood pH at 7.5-8.0

Question 5

Mx of benzodiazepine OD

Answer 5

Flumazenil