Hormones and Social Behaviour Flashcards
What are the 6 steps in WATER soluble hormone cell alteration
1 - water hormones bind to membrane receptors
2 - binding activates G protein
3 - G protein activates adenylyl cyclase
4 - Adenylyl cyclase causes ATP to convert to cAMP
5 - cAMP activates protein kinases
6 - protein kinases phosphorylates proteins in cytoplasm
In water-soluble hormone cell alteration, what happens after the hormone binds to receptors?
G protein is activated
In water-soluble hormone cell alteration, what happens when the G protein is activated?
adenylyl cyclase is activated
In water-soluble hormone cell alteration, what happens with adenylyl cyclase is activated?
Causes ATP to convert to cAMP
what is cAMP?
a secondary messenger in the water-soluble hormone pathway
In water-soluble hormone cell alteration, what does cAMP activate?
Protein kinases
In water-soluble hormone cell alteration, what does protein kinases do?
Phosphorylates proteins in cytoplasm
In water-soluble hormone cell alteration, what happens when proteins in the cytoplasm are phosphorylated?
proteins are activated and can alter cell activity
what are the 4 steps in lipid-soluble hormone cell alteration?
1 - lipid-soluble hormone DIFFUSES through plasma membrane
2 - hormone binds to receptor in cytoplasm - forms receptor-hormone complex
3 - receptor-hormone complex enters nucleus - triggers gene transcription
4 - transcribed mRNA is translated into proteins - alter cell activity
In lipid-soluble hormone cell alteration, what is the first step?
hormone diffuses through plasma membrane
In lipid-soluble hormone cell alteration, what happens after the hormone has diffused through membrane?
Binds to receptors in cytoplasm
In lipid-soluble hormone cell alteration, when hormones bind to cytoplasm receptors, what happens?
a receptor-hormone complex is formed
In lipid-soluble hormone cell alteration, what does the receptor-hormone complex do?
enters nucleus
triggers gene transcription
In lipid-soluble hormone cell alteration, what happens to the transcribed mRNA?
it is translated into proteins
these proteins alter cell activity
In lipid-soluble hormone cell alteration, what alters cell activity in the final step?
proteins