Hormones And Nephron Flashcards
Angiotensin II
Increases renin, increases NaCl and H2O reabsorption
Affect proximal tubule, thick ascending limb, and distal tubule/collecting duct
Aldosterone
Increases angiotensin II and K+ in plasma
Affects think ascending limb, DT, and CD
Will increase NaCl and H2O reabsorption
Decreases K+ reabsorption
ANP, BNP, urodilatin
Increases ECFV (extra cellular fluid volume)
Affects CD
Decreases H2O and NaCl reabsorption
Uroguanylin and guanylin
Stimulated by ingestion of NaCl
Affects PT and CD
Will decrease H2O and NaCl reabsorption
Sympathetic nerves
Decreases ECFV
Acts on PT, TAL, DT/CD
Will increase NaCl and H2O reabsorption
Dopamine
Increases ECFV
Acts on PT
Decreases H2O and NaCl reabsorption
AVP
Stimulated by increased plasma Osmolality and decreased ECFV
Acts on DT/CD
Increases H2O reabsorption
Furosemide
Thick ascending loop
Inhibits NaCl reabsorption by gifting for Cl-‘s spot in the carrier
ADH
Collecting duct
Made permeable to water
Thiazides
Cortical diluting segment of DCT
Inhibits reabsorption of Na and Cl and will enhance calcium reabsorption
Causes natriuresis and decreased BV/BP
K+ sparing spironolactone
Inhibits Na/K+ exchanged in DT and CD to promoter K+ retention and Na/H2O loss
Hypotensive effect