hormone signalling Flashcards

1
Q

specificity of signalling is achieved by

A
  1. chemically distinct hormones
  2. specific receptors for each hormone
  3. distinct distribution of receptors across target cells
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2
Q

chemical nature of hormones

A
  • modified amino acids
  • steroids
  • peptides
  • proteins
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3
Q

modified amino acid hormones are derived from

A

tyrosine and tyramine

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4
Q

examples of modified amino acid hormones

A

adrenaline and thyroid hormones

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5
Q

steroid hormones are derived from

A

cholesterol

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6
Q

examples of steroid hormones

A

cortisol, progesterone and testosterone

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7
Q

peptide hormones are derived from

A

larger precursor proteins

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8
Q

examples of peptide hormones

A

adrenocorticotrophic hormone, anti-diuretic hormone and oxytocin

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9
Q

example of protein hormones

A

insulin

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10
Q

SIGNALLING TYPES

A
  • autocrine
  • paracrine
  • endocrine
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11
Q

autocrine signalling

A

cell is both the originator and recipient of the signalling molecules

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12
Q

paracrine signalling

A

the signalling molecules are produced in a cell which then diffuse over short distances in the interstitial fluid and exert there function on target cell which are close by

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13
Q

endocrine signalling

A

the signalling molecule produced by a cell are released into the bloodstream and act on an organ distant to the site of production

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