hormone signalling Flashcards
specificity of signalling is achieved by
- chemically distinct hormones
- specific receptors for each hormone
- distinct distribution of receptors across target cells
chemical nature of hormones
- modified amino acids
- steroids
- peptides
- proteins
modified amino acid hormones are derived from
tyrosine and tyramine
examples of modified amino acid hormones
adrenaline and thyroid hormones
steroid hormones are derived from
cholesterol
examples of steroid hormones
cortisol, progesterone and testosterone
peptide hormones are derived from
larger precursor proteins
examples of peptide hormones
adrenocorticotrophic hormone, anti-diuretic hormone and oxytocin
example of protein hormones
insulin
SIGNALLING TYPES
- autocrine
- paracrine
- endocrine
autocrine signalling
cell is both the originator and recipient of the signalling molecules
paracrine signalling
the signalling molecules are produced in a cell which then diffuse over short distances in the interstitial fluid and exert there function on target cell which are close by
endocrine signalling
the signalling molecule produced by a cell are released into the bloodstream and act on an organ distant to the site of production