diabetic retinopathy Flashcards

1
Q

defintion

A

disease of the retina caused by diabetes

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2
Q

diabetic retinopathy

A

is the commonest cause of new onset blindness in those between 20-65

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3
Q

pathophysiology

A

chronic hyperglycaemia damages the tiny blood vessels in the retina, this can cause the blood vessels to leak fluid or haemorrhage and in its most advances stage can cause new abnormal blood vessels to proliferate on the surface of the retina

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4
Q

function of the retina

A

detects light and converts it to signals sent through the topic nerve

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5
Q

retinal haemorrhages described as

A

dot blot or flame haemorrhages

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6
Q

cotton wool spots on retina are

A

areas of ischaemia

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7
Q

hard exudates on retina are

A

lipid breakdown products

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8
Q

IRMA stands for

A

intra-retinal microvascular abnormalities which means abnormal but patent blood vessels

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9
Q

stages of retinopathy

A
  1. mild non-proliferate
  2. moderate non-proliferative
  3. severe non-proliferative
  4. proliferative
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10
Q

mild-non proliferative retinopathy is

A

also known as background retinopathy where on ophthalmoscopy there are mild abnormalities but person has no symptoms

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11
Q

maculopathy is

A

a manifestation of diabetic retinopathy, results in oedema and exudates involving the macula

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12
Q

diabetic maculopathy is a

A

symptomatic manifestation of non-proliferative retinopathy

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13
Q

symptoms of maculopathy

A

blurred vision, decreased acuity, visual distortion

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14
Q

maculopathy is the

A

number one cause of blindness in patients with diabetic retinopathy

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15
Q

the macula is the

A

central area of the retina which provides central vision, in the centre of the macula is the fovea which contains the higher concentration of cones therefore has the clearest vision of all

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16
Q

retinopathy and maculopathy are

A

graded separately

17
Q

retinal grading

A
R0
R1
R2
R3
R4
18
Q

R0

A

no diabetic retinopathy

19
Q

management of R0

A

rescreen in 12 months

20
Q

R1

A

background diabetic retinopathy, there are no symptoms but one or more of the following is present

  • dot haemorrhages
  • hard exudates
  • blot haemorrhages
  • micro aneurysms
  • cotton wool spots
  • flame haemorrhages
21
Q

management of R1

A

prescreen in 12 months

22
Q

R2

A

moderate non-proliferative retinopathy with four or more blot haemorrhages in one hemi-field only

23
Q

management of R2

A

prescreen in 6 months

24
Q

R3

A

severe non-proliferative diabetic retinopathy with any of the following features:

  • four or five blot haemorrhages in both superior and inferior semi-fields
  • venous bleeding
  • IRMA
25
Q

management of R3

A

refer to ophthalmology

26
Q

R4

A

profilerative diabetic retinopathy with any of the following features:

  • active new vessels
  • vitreous haemorrhage
27
Q

management of R4

A

referral to ophthalmology who will treat

28
Q

macular grading

A

MI OR M2

29
Q

M1

A

any hard exudates within a radius of greater than 1 but less than 2 disc diameters of the centre of the fovea, prescreen in 6 months

30
Q

M2

A

any hard exudates or blot haemorrhages within a radius of more than one disc diameters of the centre of the moves, refer to ophthalmology

31
Q

investigations for diabetic retinopathy

A

ophthalmoscopy and optical coherence tomography

32
Q

management

A
  • anti-vascular endothelial growth factor injections (anti-VEGF)
  • laser therapy
33
Q

other eye pathologies in diabetics

A

cataracts, glaucoma

34
Q

cataracts

A

opacity of the crystalline lens causing a haziness/ cloudiness of vision, often the intimal presentation of cataracts is lekocoria (white pupil)

35
Q

glaucoma

A

group of eye diseases that are caused by intra-ocular hypertension which damages the optic nerve