Hormonal Coordination In Humans Flashcards
What is negative feedback?
Negative feedback is a homeostatic mechanism.
It is the regulation of internal conditions to maintain conditions for function in response to an interanl or external change
What are hormones?
Chemical messangers which ae secreted by glands into the bloodstream and transmitted to a target organ
What is the function of thyroxine
Stimulates basal metabollic rate and growth
What are the differences between the nervous system and the endocrine system?
The nervous system releases electrical impulses which are transmitted along neurones. Reflexes from the nervous system are rapid and automatic,they do not last long
The endocrine system releases hormones which are transmitted along the bloodstream
The hormones are secreted slowly but they are long-lasting
Which gland detects changes in thyroxine levels in the blood?
Hypothalamus
Which gland secretes TRH into the bloodstream?
Hypothalamus
Which gland detects TRH levels in the blood stream?
Pituitary gland
Which gland secretes TSH into the bloodstream?
Pituitary gland
Which gland detects TSH levels in the bloodstream?
Thyroid gland
What is the function of the thyroid gland?
Secretes thyroxine which stimulate basal metabolic rate and growth
Which gland secretes thyroxine into the bloodstream?
Thyroid gland
Explain how thyroxine works as a part of the negative feedback loop
The hypothalamus in the brain detects the low levels of thyroxine in the bloodstream. This stimulates the secretion of TRH from the hypothalamus into the bloodstream
The TRH is detected by the pituitary gland. This stimulates the secretion of TSH from the pituitary gland
The TSH is detected by the thyroid gland. This stimulates the secretion of the thyroxine hormone, increasing basal metabollic rate
When the thyroxine levels in the bloodstream rise too high, this is detected by the hypothalamus in the brain, and this inhibits the secretion of TRH from the hypothalamus into the bloodstream.
The pituitar gland detect the low levels of TRH, this inhibits the secretion of TSH from the pituitary gland into the bloodstream
Then the thyroid gland detects the low levels of TSH, this inhibits the secretion of thyroxine into the bloodstream.
This fluctuation of thyroxine secretion about the normal is the negative feedback loop
What happens when there is a high level of the thyroxine hormone in the bloodstream
Negative feedback:
The hypothalamus in the brain detects the high levels of thyroxine in the bloodstream, this inhibits TRH secretion form the hypothalamus into the bloodstream
The reduced levelsof TRH are detected by the pituitary glands. This then inhibits TSH secretion from the pituitary gland into the bloodstream
The reduced levels of TSH are detected by the thyroid gland, this stimulates the thyroid to secrete less thyroxine into the blood stream, reducing basal metabollic rate
Which gland detects levels of thyroxine in the blood stream?
Hypothalamus
Which gland detects levels of TRH in the bloodstream?
Pituitary gland