Homeostasis Flashcards
What is homeostasis?
The relative constancy of the body’s internal environment regardless of the conditions in the external environment.
What is cybernetics?
The science of control systems, i.e., self-regulating systems that operate by means of feedback mechanisms.
What is a feedback system?
A mechanism in which an input stimulus causes an output response that ‘feeds back’ to the initial input.
What are the three components of a feedback system?
- Detector eg hypothalamus
- Regulator eg pituitary gland
- Effector eg thyroid gland
What is negative feedback?
A mechanism in which the effect of deviation from the normal condition triggers a sequence of events that restores the system to its set point and afterwards the mechanism is switched off.
What is positive feedback?
A mechanism in which the effect of deviation from the normal condition intensifies the original response such that the change tends to proceed in the same direction as the initial stimulus.
Why are positive feedback mechanisms few in biological systems?
Because positive feedback mechanisms cause larger deviations from the normal set point and may lead to unstable conditions and extreme states.
What is the function of the liver in glucose regulation?
The liver maintains a steady blood glucose concentration by conversion of glucose to glycogen (if above the norm) and vice versa (if below the norm), under the influence of hormones.
What is gluconeogenesis?
The formation of glucose from non-carbohydrate sources.
How does adrenaline affect blood glucose levels?
Adrenaline causes hydrolysis of glycogen to glucose during acute stress or excitement, increasing glucose concentration in blood.
What causes insulin-dependent diabetes?
Insufficient secretion of insulin.
What causes insulin-independent diabetes?
Insensitivity of cells to insulin.
What are the symptoms of diabetes mellitus?
High blood sugar, glycosuria, frequent copious urination, abnormal thirst, visual disturbances, itching of genitals, fatigue, rapid weight loss, and drowsiness.
What is the function of the liver in maintaining blood glucose concentration?
The liver maintains a steady blood glucose concentration by conversion of glucose to glycogen (if above the norm) and vice versa (if below the norm), under the influence of hormones.
What are the functions of the liver?
The liver maintains a steady blood glucose concentration, regulates amino acids and proteins, regulates lipids, forms red blood cells and lymphocytes in foetus and breaks down worn out red blood cells in adults, synthesizes plasma proteins, produces bile, stores fat soluble vitamins and water soluble vitamins, stores minerals, stores blood, destroys hormones, and detoxifies poisonous substances.
What are the main reactions of the ornithine cycle?
The amino group of an amino acid is removed and reacts with hydrogen to form ammonia, ammonia reacts with carbondioxide to form carbamoyl phosphate, carbamoyl phosphate reacts with ornithine to form citrulline, citrulline diffuses into the cytoplasm and reacts with aspartate to form argininosuccinate, argininosuccinate splits into arginine and fumarate, arginine is hydrolysed to form urea and ornithine, and urea formed is carried by the blood stream to the kidneys for excretion in urine.
What is atherosclerosis?
The narrowing of arteries usually due to lipid build up.
What is endothermy?
The ability of animals to maintain a constant body temperature.