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IHO Week 4 > Hodgkin Lymphoma - Krafts > Flashcards

Hodgkin Lymphoma - Krafts Flashcards

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1
Q

What are the key characteristic cells common in Hodgkin Lymphoma?

A

Reed-Sternberg Cells (Large Nucleoli = Owl’s Eye) => Malignant

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2
Q

What are the characteristics of Hodgkin Lymphoma?

A

Contiguous Spread
Younger Patients (20s)
Good Prognosis

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3
Q

What are the 5 subtypes of Hodgkin Lymphoma?

A

1) Nodular Lymphocyte-Predominance Hodgkin Lymphoma
2) Nodular Sclerosis
3) Lymphocyte Rich
4) Mixed Cellularity
5) Lymphocyte Depletion

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4
Q

Why is Nodular Lymphocyte-Predominance Hodgkin Lymphoma non-classical in terms of subtyping?

A

Only one lymph node involved
YOUNG patients
GREAT prognosis

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5
Q

What are the characteristics of Nodular Lymphocyte-Predominance Hodgkin Lymphoma?

A

Asymtomatic young male with cervical lymphadenopathy
Good Prognosis in early stage
B-Cell Origin
Popcorn Cells

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6
Q

What are the characteristics of Nodular Sclerosis Hodgkin Lymphoma?

A

MOST COMMON subtype

Good Prognosis in early stage

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7
Q

What are the key characteristic cells common in Nodular Lympho-cyte Predominance Hodgkin Lymphoma?

A

Popcorn Cells (abnormal Reed-Sternberg cells)

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8
Q

What are the key characteristic cells common in Nodular Sclerosis Hodgkin Lymphoma?

A

Lacunar Cells (cytoplasm retracts with fixation)

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9
Q

What are the characteristics of Mixed Cellularity Hodgkin Lymphoma?

A

Worse Prognosis due to dissemination upon presentation (later diagnosis)
Mixture of Background Cells (Eosinophils, Plasma Cells, Histiocytes)

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10
Q

What are the key characteristic cells common in Mixed Cellularity Hodgkin Lymphoma?

A

Classic Reed-Sternberg Cells

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11
Q

What are the characteristics of Lymphocyte-Rich Hodgkin Lymphoma?

A

Uncommon

Usually localized at presentation

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12
Q

What are the key characteristic cells common in Lymphocyte-Rich Hodgkin Lymphoma?

A

Popcorn Cells

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13
Q

What are the characteristics of Lymphocyte Depletion Hodgkin Lymphoma?

A

Rare
Disseminated at Presentation
Collagen or Reticulin Background

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14
Q

What are the key characteristic cells common in Lymphocyte Depletion Hodgkin Lymphoma?

A

Classic Reed-Sternberg Cells

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15
Q

What is the treatment for Hodgkin Lymphoma?

A

Surgery
Chemotherapy
Radiation

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16
Q

What is the prognosis for Hodgkin Lymphoma?

A

Depends on Stage

17
Q

What is the danger in treating a patient with chemotherapy?

A

Secondary Malignancies

- like skin cancer, breast cancer, leukemia

IHO Week 4 (15 decks)

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