HMP shunt Flashcards
1
Q
Enzyme in the irreversible rate-limiting step in the HMP shunt?
A
G6PD
2
Q
Functions of the HMP shunt?
A
Generate NADPH
Generate R6P for nucleotide synthesis
3
Q
Inhibitor of G6PD?
A
NADPH
4
Q
What is NADPH used for?
A
Reductive biosynthesis
Detoxification reactions
Gluthathione reduction
Generation of ROS
Synthesis of NO
5
Q
What vitamin is required for transketolase activity?
A
Thiamine
