HLA's Flashcards
HLA-A3
Haemachromatosis
HLA-A-3101 + HLA-B1502
Carbamazepine hypersensitivity (euro/asians more frequent)
HL-B27
Ankylosing spondylitis, Reiter’s syndrome. acute anterior uveitis.
HLA-B27-01
Protective late against HIV
HLA-B3503
Susceptible to HIV
HLA -B51
Behcet’s disease
HLA-B54 + MEFV
Sweet’s syndrome
HLA-B5701
Abacavir hypersensitivity, Protective early against HIV
HLA-B5801
Allopurinol DRESS syndrome (Han Chinese, Thai, Korean background)
HLA-DQ1
Narcolepsy
HLA-DQ2/8
Coeliac disease
HLA-DR1
Bronchiectasis
HLA-DR2
Narcolepsy, Goodpasture’s, SLE
HLA-DR3
Dermatitis herpetiformis, Sjogren’s syndrome, Primary billary cirrhosis, Autoimmune hepatitis, SLE
HLA-DR4
T1DM (also HLA-DR3), RA
HLA-DRB1-0301
SLE
HLA-DRB1-04
RA - shared epitope, GCA/PMR spectrum