HIV/Virus Flashcards

1
Q

How does prevalence increases?

A

people get diseases faster and people live longer with the disease

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2
Q

How does prevalence decreases?

A

people diseases at a slower late, people are cured, people with disease die

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3
Q

equation for incidence

A

no. new infections/total time experienced for people followed

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4
Q

How does HIV spread?

A

mucocutaneous contact with blood, semen, vaginal secretion, injection and perinatal transmission (pregnancy, childbirth and breast feeding)

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5
Q

HIV preventions

A

treatment, prexposure to porphylaxis (PrEP), male circumcision

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6
Q

What enhances HIV transmission?

A

viral load, disease stage (acute HIV and end stange), male circumcision status, co-infection with STIs

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7
Q

Risk groups for HIV

A

Men sex with men, people inject drugs, sex workers and sexual partners of these people

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8
Q

HIV prevalence is? incidence?

A

increase and decrease

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9
Q

What does HIV virus consist of?

A

lipid bilayer, 2 RNA genome, surface antigen gp120 and gp41, gag gene, pol (integrase, protease, RT), non-structural and regulatory gene

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10
Q

lymphotropic receptor

A

CXCR4

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11
Q

MACROTROPHIC receptor

A

CCR5

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12
Q

Reverse Transcritase Inhibitor

A

Zidovudine –absence of 3’OH

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13
Q

Antiviral therapy

A

RTi, Pi and Integrase i

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14
Q

initial target of HIV

A

Langerhans cell

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