HIV and AIDS Flashcards
1
Q
How can you measure immune system status?
A
CD4 count
- the lower the number of CD4 cells, the less natural immunity
should be between 400 and 1600 cells, any less than 350 and ART is needed
2
Q
Why can protease inhibitors be worse anti-retrovirals compared to NRTIs?
A
as protease inhibitors are CYTP450 inhibitors so extensive potential for DDIs whereas NRTIs are not
3
Q
Protease inhibitors are always boosted with what drug?
A
Ritonavir (this has no other use other to boost PI)
4
Q
ART is linked to what? and so this significantly reduces adherence
A
lipodystrophy (fat redistribution)
5
Q
Give an example of an integrate inhibitor:
A
Raltegravir
