HIV Flashcards
Pneumocystis jiroveci is a rare pneumonia associated with which group of people?
HIV positive individuals
In areas where HIV has the highest prevalence, what is the primary mode of transmission?
Heterosexual intercourse
What is vertical transmission?
Infection passed parent to child
What is the most common strain of HIV-1 in Europe?
HIV-1 M (clade B)
other strains are N, O, P
Depletion of which cell type is a hallmark of HIV infection?
CD4 lymphocytes
Which of the followings is not a stage of HIV infection?
A) AIDS
B) Acute infection
C) Humoral immunity
D) Clinical latency
C) Humoral immunity
Which anti-retroviral drugs result in chain termination of DNA synthesis by mimicking nucleotides?
A) Nucleoside reverse transcriptase inhibitors (NRTIs)
B) Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
C) Protease inhibitors (PIs)
D) Integrase inhibitors (IIs)
E) Fusion inhibitors (FIs)
F) CCR5 blockers
A) Nucleoside reverse transcriptase inhibitors (NRTIs)
Which anti-retroviral drugs inhibit DNA synthesis by direct non-competitive binding to reverse transcriptase enzyme??
A) Nucleoside reverse transcriptase inhibitors (NRTIs)
B) Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
C) Protease inhibitors (PIs)
D) Integrase inhibitors (IIs)
E) Fusion inhibitors (FIs)
F) CCR5 blockers
B) Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
Which anti-retroviral drugs prevent cleaving of protein precursors that are vital for HIV maturation?
A) Nucleoside reverse transcriptase inhibitors (NRTIs)
B) Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
C) Protease inhibitors (PIs)
D) Integrase inhibitors (IIs)
E) Fusion inhibitors (FIs)
F) CCR5 blockers
C) Protease inhibitors (PIs)
Which anti-retroviral drugs bind to GP41?
A) Nucleoside reverse transcriptase inhibitors (NRTIs)
B) Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
C) Protease inhibitors (PIs)
D) Integrase inhibitors (IIs)
E) Fusion inhibitors (FIs)
F) CCR5 blockers
E) Fusion inhibitors (FIs)
Which anti-retroviral drugs inhibit chemokine receptors used by HIV to gain entry to host cells?
A) Nucleoside reverse transcriptase inhibitors (NRTIs)
B) Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
C) Protease inhibitors (PIs)
D) Integrase inhibitors (IIs)
E) Fusion inhibitors (FIs)
F) CCR5 blockers
F) CCR5 blockers
Which anti-retroviral drugs prevent viral DNA from integrating with host cellular DNA?
A) Nucleoside reverse transcriptase inhibitors (NRTIs)
B) Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
C) Protease inhibitors (PIs)
D) Integrase inhibitors (IIs)
E) Fusion inhibitors (FIs)
F) CCR5 blockers
D) Integrase inhibitors (IIs)
How might valacyclovir (herpes medication) help fight HIV-1?
Prevents it from replicating
Which HIV prophylaxis drug is taken before intercourse with an HIV positive partner?
PrEP
Pre-Exposure Prophylaxis
Which HIV prophylaxis drug is taken after suspected exposure to HIV positive body fluid?
PEP
Post Exposure Prophylaxis
