HIV

Question 1

What is the normal WBC count?

Answer 1

4,000-11,000 uL

Question 2

When WBC count is low this indicates?

Answer 2

Immunosuppression

Question 3

When WBC count is high, this indicates?

Answer 3

Infection

Question 4

What are the three distinction of metastasis?

Answer 4

Localized
Disseminated
Systemic

Question 5

What are the symptoms of SIRS?

Answer 5

Two of more of the following:
WBC > 12,000/uL + 10% bands
100.4 F or 96.8F (lower temp happens in elderly and immunosuppressed)
Tachycardia (>100)
Tachypnea (>20)

Question 6

What should you do if you suspect an infection?

Answer 6

Do a pan culture

Question 7

What is a pan-culture?

Answer 7

Culture everywhere possible to get a potential source of infection

Question 8

What is the cause of HIV?

Answer 8

Retrovirus that causes immunosuppression

Question 9

What is the pathophysiology of HIV?

Answer 9

HIV directly infects CD4+ T-cell. The viral HIV binds to CD4 protein and CCR5 to cause infection by injection of viral protein. Replication of the viral DNA occurs

Question 10

What is a viral load?

Answer 10

It is the amount of HIV virus in the blood

Question 11

What are means of transmission of HIV?

Answer 11

Vaginal, anal, and oral sex. Injection of drugs. Breast milk. Risk behavior

Question 12

What are the acute symptoms of HIV?

Answer 12

Flu-like symptoms

General malaise

Question 13

What are the asymptomatic symptoms of chronic HIV?

Answer 13

Feel fine
CD4 is above 500/uL
Viral load is low

Question 14

What are the symptomatic symptoms of chronic HIV?

Answer 14

CD4 cells are 200-500/uL
Viral load is high
Thrush is present
Oral hairy leukoplakia

Question 15

Describe the transition HIV to AIDs

Answer 15

CD4 t-cells are below 200/uL

Viral load is high

Question 16

What is the diagnostic immune criteria?

Answer 16

CD4 t-cell is 200 cell/uL
Get an opportunistic infection
Get an opportunistic cancer