HIV

Question 0

Viruses belong to the subfamily Oncovirinae

Answer 0

HTLV1
HTLV-2
HTLV-5

Question 1

HIV belongs to what subfamily?

Answer 1

Lentivirinae

Question 2

gp 120- aid in the fusion and attachment of HIV to CD4+ cells

Answer 2

Env Gene

Question 4

Other name for HIV

Answer 4

HTLV-3 (human Tcell lymphotropic virus type 3)
LAV (Lymphadenopathy associated virus)
ARV (AIDS associated retrovirus)

Question 5

Most common subtype of Group M

Answer 5

Subtype C

Question 6

Three layer structure of HIV

Answer 6

P24
gp41
gp120

Question 7

HIV Naked or enveloped?
Icosahedral or complex?
With or without spikes?

Answer 7

Envelope
Icosahedral
With spikes

Question 8

Enzyme present in Retroviridae

Answer 8

Reverse transcriptase

Question 9

Diagnostically important proteins

Answer 9

p24
gp41
gp120
gp160

Question 11

Transcribe RNA to DNA

Answer 11

Reverse transcriptase

Question 12

Strains that can infect both macrophages and T cells

Answer 12

M tropic or R5

Question 13

The three main structural gene of HIV

Answer 13

Env gene
Gag gene
Pol gene

Question 15

Viral genetic material that is incorporated to the DNA of the host cell

Answer 15

Provirus

Question 16

Group antigen gene that is found in nucleocapsid

Answer 16

p15
p17
p24

Question 17

Receptor to the host

Answer 17

CD4

Question 18

Positive dried smear of HIV remain infectious for? How about HBV smear?

Answer 18

3days

7days

Question 19

HIV viruses that preferentially infect T cells

Answer 19

T tropic or X4 strain

Question 20

Inserts viral DNA to host DNA

Answer 20

Integrase

Question 22

Chemokine receptor of HIV required to enter T cells

Answer 22

CXCR4

Question 23

This is used to inactivate HBV and HIV

Answer 23

HBV- 10% bleach for 10mins

HIV- 10% bleach for 3mins

Question 24

First antibody to be produced following HIV infection

Answer 24

anti p24

Question 26

Confirmatory test for HIV

Answer 26

Western blot

Question 27

Receptor to the virus

Answer 27

gp120

Question 28

MOT of HIV

Answer 28

Sexual
Perinatal
Parenteral

Question 30

End stage of HIV infection

Answer 30

AIDS

Question 31

Treatment for HIV that involves aggressive combination therapy

Answer 31

HAART | Highly active anti retroviral therapy

Question 32

Classify HIV-1 and HIV-2 according to distribution

Answer 32

HIV1 global or pandemic | HIV2 west Africa

Question 33

Testing is often done at _____, ______,&_______ after exposure to find out if a person is infected with HIV

Answer 33

6wks 3months 5months

Question 34

Screening test for HIV

Answer 34

Elisa RIA Agglutination test

Question 35

Chemokine receptor of HIV required to enter macrophages

Answer 35

CCR5

Question 45

Cleaves structural protein located in the core near the nucleic acid

Answer 45

Protease

Question 46

The three subgroups of HIV 1

Answer 46

Group M Group N Group O