HIV

Question 1

NRTI toxicity

Answer 1

No cyp interactions 
Lactic acidosis
Hepatomegaly
RENAL DOSE (except abacavir)

Question 2

Ziagen

Answer 2

Abacavir

NRTI

Question 3

Epivir

Answer 3

Lamivudine

NRTI

Question 4

Meds also used for hep b

Answer 4

Lamivudive (epivir hbv)
Entecavir- (empty stomach)
Tenofovir (viread (for both))

Question 5

Emtriva

Answer 5

Emtricitabine

NRTI

Question 6

Viread

Answer 6

Tenofovir disoprixil fumarate
Nephro osteo fanconi
NRTI

Question 7

Tenofovir alafenamide

Answer 7

NRTI

Question 8

Retrovir

Answer 8

Zidovudine
NRTI
Hematologist toxicity (macrocyclic anemia) and myopathy
IV for labor in preganancy

Question 9

Stavudine

Answer 9

NRTI

Not recommended

Question 10

Didanosine

Answer 10

NRTI
Not recommended
Empty stomach

Question 11

NNRTI toxicity

Answer 11

NO RENAL DOSE
CYP3A4 inducers
Hepatotoxicity
Rash (most with nevirapine)

Question 12

NNRTI food

Answer 12

With : etravirine, rilpivirine

W/o : efavirenz (also QHS)

Question 13

Edurant

Answer 13

Rilpivirine
NNRTI
With food!!!
QTC, depression/suicide, insomnia

Question 14

Sustiva

Answer 14

Efavirenz
NNRTI
Without food!!
Bedtime! QTC!
Psychiatric symptoms

Question 15

Doravirine

Answer 15

Pifeltro

NNRTI

Question 16

Nevirapine

Answer 16

Viramune
NNRTI
More rash than others

Question 17

Etravirine

Answer 17

Intelence
NNRTI
With food

Question 18

Protease inhibitors

Answer 18

Navir 
CYP3a4 inhibitors!
NO RENAL!!
Hepatotoxicity 
Always give with booster (ritonavir or cobicistat)
Metabolic: HLD lipohyperttrophy
Take with food! (GI upset)
CVD risk, bleeding, ECG changes
Rash

Question 19

Prezista

Answer 19

Darunavir
Protease inhibitor
SULFA!!!

Question 20

Reyetaz

Answer 20

Atazanavir
Protease inhibitor
Hyperbilirubinemia!! (Bananavir)
Needs acid!!

Question 21

Lexiva

Answer 21

Fosamprenavir
Protease inhibitor
SULFA!!
Suspension- NO FOOD!

Question 22

Crixivan

Answer 22

Indinavir
Protease inhibitor 
Nephrolithiasis
Empty stomach
Water! Kidney stones!

Question 23

Kaletra

Answer 23

Lopinavir/ritonavir
Protease inhibitor
HLD (esp. TG)
With food

Question 24

Viracept

Answer 24

Nelfinavir
PI
Do not boost!

Question 25

Invirase

Answer 25

Saquinavir PI Must give with ritonavir QTc, nausea

Question 26

Tipranavir

Answer 26

Aptivus PI GIVE WITH RITONAVIR SULFA!!!

Question 27

Tyboost

Answer 27

Cobicistat | Take with food

Question 28

Ritonivir

Answer 28

Novir PI/ booster Take with food

Question 29

Integrate inhibitor toxicity

Answer 29

Tegravir NO renal except: stribild (don’t start if <70) and genvoya/biktarvi (don’t start if <30) No cyp interactions Increased CPK, HA, insomnia SEPARATE FROM DIVALENT CATIONS

Question 30

Elvitegravir

Answer 30

Insti | With food

Question 31

Bictegravir

Answer 31

Insti

Question 32

Tivicay

Answer 32

Dolutegravir Insti Don’t use in pregnancy

Question 33

Isentress

Answer 33

Raltegravir Insti Myopathy/rhabdo

Question 34

Maraviroc

Answer 34

``` CCR5 antagonist Stage 1 (stops entering cell) Blocks human cell receptor Need CCR5 positive tropism test Need negative CXCR4 or mixed Hepatotoxicity ```

Question 35

Fuzeon

Answer 35

Enfuvirtide Fusion inhibitor (stage 2) SC

Question 36

Trogarzo

Answer 36

Ibalizumab | MDR HIV

Question 37

Megace

Answer 37

Megesterol | Anorexia with aids

Question 38

Marinol

Answer 38

Drinabinol | Anorexia with aids

Question 39

Prep

Answer 39

Truvada po QD Assess hiv neg before starting and Q3 months 90 at a time max (60 if per RPH protocol)

Question 40

Pep

Answer 40

Truvada + raltegravir or dolutegravir within 72 hours Test at baseline, 4-6 wk, 3 month and 6 month

Question 41

Biktarvy

Answer 41

Bictegravir, emtricitabine, TAF Don’t start crcl<30

Question 42

Triumeq

Answer 42

Dolutegravir, abacavir, lamivudine

Question 43

Truvada

Answer 43

Emtricitabine, TDF

Question 44

Descovy

Answer 44

Emtricitabine, TAF

Question 45

Stribild

Answer 45

Elvitegravir, cobicistat, emtricitabine, TDF Don’t start crcl<70

Question 46

Genvoya

Answer 46

Elvitegravir, cobicistat, emtricitabine, TAF Don’t start crcl<30

Question 47

Atripila

Answer 47

Efavirenz, emtricitabine, TDF | NNRTI based so not first line

Question 48

Complera

Answer 48

Rilpivirine, emtricitabine, TDF | NNRTI based so not first line

Question 49

Odefsey

Answer 49

Rilpivirine, emtricitabine, TAF | NNRTI based so not first line

Question 50

First line

Answer 50

Triumeq, biktarvy Or combos of Tivicay/isentress with truvada/descovy INSTI based

Question 51

Epzicom

Answer 51

Abacavir/lamivudine

Question 52

Aptivus

Answer 52

Tipranavir PI Sulfa allergy

Question 53

Sulfa allergy

Answer 53

Lexiva (fosamprenavir) Prezista (darunavir) Aptivus (tipranavir) *all protease inhibitors

Question 54

Paxlovid

Answer 54

Nirmatrelvir/ritonovir | Covid 19- mild-mod- at least 12 yrs and 40kg at risk of progression to severe

Question 55

Didanosine

Answer 55

Videx ec NRTI Empty stomach

Question 56

Selzentry

Answer 56

Maraviroc | Entry inhibitor

Question 57

Zidovudine ADR major

Answer 57

Normocytic anemia

Question 58

Vitekta

Answer 58

Elvitegravir WITH FOOD!

Question 59

Entecavir v etravirine

Answer 59

Entecavir: NRTI Etravirine: NNRTI

Question 60

Zepatier

Answer 60

Grazoprevir + elvasvir No regard to food Hep C

Question 61

Which PI needs empty stomach

Answer 61

Crixivan (indinavir) Water though! Kidney stones *unles with ritonavir* And fosamprenavir Susp

Question 62

Viramune

Answer 62

Nevirapine NNRTI More rash

Question 63

Exviera

Answer 63

Dasabuvir | Hep c

Question 64

Evotaz

Answer 64

Atazanavir (reyetaz) + tybost (cobicistat)

Question 65

Prezcobix

Answer 65

Prezista (darunavir) + cobicistat

Question 66

Baraclude

Answer 66

Entecavir | Hep B

Question 67

Hepsera

Answer 67

Adefovir | NRTI hep B