HIV Flashcards

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1
Q

What does HIV stand for

A

Human iummuodeficiency virus

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2
Q

How is HIV transmitted

A
  • unprotected sex
  • infected needles
  • HIV positive mothers to children during pregnancy and breast feeding
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3
Q

Where is HIV found

A

In some body fluids: semen and breast milk

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4
Q

What is the emergency treament for HIV

A

Post exposure prophylaxis - 72h may stop a person getting infected

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5
Q

What does AIDS stand for

A

Acquired immune deficency syndrome

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6
Q

How does HIV cause symptoms of AIDS

A
  • HIV directly attacks T helper cells
  • HIV die after releasing replicate virus casuing T helper cells to die
  • number of T helper cels decrease
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7
Q

Wht does low levels of T helper cells means

A
  • immune response not stimulated such as B cells, Cytotoxic T cells, phagocytosis not being stimulated
  • means the infected person will experience a significant number of infections and other life threating illnesses which kills them
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8
Q

How do you test for HIV

A
  • Detect the presence if HIV antigens or antibodes to HIV or detct the gentic materil of HIV in the sample
  • elisa test
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9
Q

After being infected wth HIV how long till HIV antibodies appear in the bloof

A

2 weeks to 6 months

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10
Q

How big is the HIV virsus

A

O.1nanometers

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11
Q

Name all the parts of the HIV virus

A
  • attachment glycoprotein
  • transmemebrne glycoprotein
  • lipid membrane
  • matrix
  • capsid
  • enzymes
  • Gentic material
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12
Q

What is the genetic material of HIV made out off

A

RNA

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13
Q

Whta is the capsid made out of

A

The protein p24

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14
Q

What enzymes are found in HIV

A
  • reverse transcriptase
  • intergrase
  • proteases
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15
Q

What type of virus is HIV

A

Retro virus

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16
Q

Why is HIV a retro virus

A
  • has RNA rather than DNA

- uses reverse transcription which makes DNA and RNA

17
Q

Decribe he life cycle of HIV in T helper cells

A

Fuse = attachmen glycoproetins on HIV sticks to CD4 which allows HIV to fuse with cell membrane of T helper cell

  1. Release = contents of HIV capsid (RNA and enzymes )released into T helper cells
  2. Reverse transcription = HIV enzyme reverse transcriptase copies HIV RNA into single DNA then double stranded DNA
  3. Intergrase = inserts HIV DNA into Th cells DNA
  4. Expression = genes in HIV DNA expressed in TH cells
  5. Infect = new HIV particle now ready to onfect other cells
18
Q

Why antibiotics ineffective Against AIDS

A