HIV 1

Question 1

What is the major nucleocapsid protein in HIV?

Answer 1

p24

Question 2

What are the 6 steps of HIV replication?

Answer 2

attachment, entry, uncoating, nucleic acid snythesis, assembly, release

Question 3

Where will you predominantly find CCR5 receptors? (make sure you understand this better)

Answer 3

macrophages

Question 4

Name the HIV drug that can be given to mother as preventation from passing to baby

Answer 4

AZT

Question 5

Name the drug that is involved in hypersensiitivity reactions

Answer 5

Abacavir

Question 6

Name the 6 classes of HIV drugs

Answer 6

1) Nucleoside Reverse Trans inhibitor (NTRI)
2) non-nucleoside RTI (NNRTI)
3) Nucleotide RTI Z(NtRTI)
4) Protease Inhibitor
5) Integrase Inhibitor
6) Fusion Inhibitor

Question 7

Name 4 of the Nucleoside Reverse Transcriptase Inhibitors

Answer 7

1) Zenovudine
2) Abacavir
3) Lamoviudine
4) Tenofivir

THEY ALL END WITH -INE OR -VIR

Question 8

Name 4 of the Nucleoside Reverse Transcriptase Inhibitors

Answer 8

the NTRIs are 
ABACAVIR
ZENOVUDINE
TENOFIVIR 
LAMMMMMIVUDINE 

THEY ALL END WITH -INE OR -VIR

Question 9

Name the Integrase inhibitor:

Answer 9

Relatigir (retaliates against the machine)

Question 10

Name the drugs with the unique mechanism

Answer 10

Maraviroc —a unique looking rock

Question 11

What should you check for when using Abacavir?

Answer 11

HLA sensitivity

Question 12

What are the 3 genes in HIV

Answer 12

ENV- gp120, and gp41
GAG- gp24 (capsid) and GP17 (MATRIX)
POL- reverse transctptase and integrase and protease (3 OF THEM)!!!!!