Histpo Review Flashcards
Describe action as an element of cytoskeleton
Associated with elements
Microvilli
Stereocilia
Locomotion (lamellipodia, filopodia, pseudopodia)
Describe microtubules as cytoskeleton elements
- tracks for dynein/ kinesin to move things within the cell
- cilia flagella for movement of cell
- Also spindle
Describe intermediate filaments as cytoskeleton elements
- adhesion (cell to cell, cell to basement membrane)
- Mechanical strength
A group of researchers studying programmed cell death knocked out the gene coding for Bcl-2 . What effect would this have on the cell?
The cell would undergo programmed cell death
A35-year old woman exophthalmos, weight loss despite eating more, and profuse sweating. Her heart rate is 180/90 and she says she always feels hot. She has been diagnosed with Graves’ disease, which is associated with excess production of T3 and T4 by the thyroid gland . What lines the follicles f the thyroid gland?
Simple cuboidal epithelium
A 19 year old woman presents to the clinic with a. History of recurrent respiratory infections. She has been told that her infections were due to a decreased ability to clear mucus from her respiratory tract. Which cells have this function?
Ciliated columnar cells
A group of researchers studying cell division need to arrest the cell in metaphase as part of their experiment. Which agent can be used to arrest the kinetochore microtubules in metaphase?
Colchicine
A young boy is brought to the clinic by his mother for a routine check up. On examination, the doctor notices that the child cannot stand up without using his upper extremities. His calves are noticeably enlarged. The child is sent for a biopsy of his calves . What is the inheritance pattern of the disorder the boy presents with?
X-linked recessive
A group of researchers were studying the effect of a new drug with similar effects as HDAC (Histone deacetylase). What type of chromatin structure would be formed as a result of this drug?
B
A research team studying protein synthesis and modification knocked out the SRP( Signal Recognition Particle) gene in a colony of mice. Which of the following functions would be impaired due to lack of SRP?
N-linked glycosylation
