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Histopathology > Histopathology Practical 5 > Flashcards

Histopathology Practical 5 Flashcards

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cholangiohepatitis

inflammation effects bile ducts and liver itself

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3
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portal triad
red: bileduct
blue : thick walled a. hepatica —> fresh blood from heart
green: portal vein

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4
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cholangiohepatitis

portal triad
limiting plate

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5
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cholangiohepatitis

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6
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cholangiohepatitis

portal triad , you can see inflammatory area compared to normal tissue

inflammatory cells: mononuclear

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7
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cholangiohepatitis

bile duucts

lymphocytes
mononuclear inflammatory cells

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8
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cholangiohepatitis

bile duucts

lymphocytes
mononuclear inflammatory cells

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9
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rubarths disease
caused by canine adenovirus 1 hepatis

enlarged and shiney liver

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10
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rubarths disease
caused by canine adenovirus 1 hepatis

portal and sinusoidal inflammatory infiltration

green arrow: cowdry A- type intranuclear inclusion body

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11
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rubarths disease
caused by canine adenovirus 1 hepatis

cowdry A- type intranuclear inclusion body

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12
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rubarths disease
caused by canine adenovirus 1 hepatis

cowdry A- type intranuclear inclusion body

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13
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rubarths disease
caused by canine adenovirus 1 hepatis

necrosis

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14
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rubarths disease
caused by canine adenovirus 1 hepatis

green : necrosis
red: not healthy liver tissue, but functional

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15
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rubarths disease
caused by canine adenovirus 1 hepatis

red area: necrosis
green : cowdry A- type intranucl. inclusion body
usually next to necrosis

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16
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rubarths disease
caused by canine adenovirus 1 hepatis

blue: apoptosis
green: cowdry A- type intranucl. inclusion body

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17
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rubarths disease
caused by canine adenovirus 1 hepatis

necrotic zone with hyperaemic rim around

you can also spot some inflamamtory cells arounds

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18
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rubarths disease
caused by canine adenovirus 1 hepatis

upper part is normal liver parenchyma

lower part is necrotic, due to viral effect–> know it is viral if you see intranuclear inclusion bodies which is shown on the arrows

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19
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Liver cirrhosis
chronic condition –> scar tissue

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20
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Liver cirrhosis
regenerative nodules

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21
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Liver cirrhosis

pseudolobulus–> smaller part of liver tissue without central vein in the middle

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22
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liver cirrhosis

pseudolobulus with azan staining
stains collagen blue

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23
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Liver cirrhosis

pseudolobule

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24
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Liver cirrhosis

bile duct proliferation

25
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Liver cirrhosis
ductal proliferation

26
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Liver cirrhosis

silver staining

27
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Paratuberculosis

enlargment in ln of mesenterica

28
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Paratuberculosis

proliferative innflammation

mucous membrane of ileum look like brain

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Paratuberculosis

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Paratuberculosis

green: enteric mucosa with some inflammatory cells, can still se villi
blue: proliferation of histocytes –> can find langhans gigant cells
proliferation due to lack of TNf alpha producton

31
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Paratuberculosis

ziehl nielsen staining to detect mycobacteria –> red

32
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Paratuberculosis

epitheloid cells

33
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parvoviral necrotic- haemorrhagic enteritis
necrotic of small intestine
enlarged ln in mesenterica

34
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parvoviral necrotic- haemorrhagic enteritis

necrotic mucosa

( payers patches ?!?!?!?!?!? says so in the video, mucosa above sunken in )

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parvoviral necrotic- haemorrhagic enteritis

necrosis

36
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parvoviral necrotic- haemorrhagic enteritis

looks like internuclear infusion bodies features, but he says in the video that you can not be sure that it is

37
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parvoviral necrotic- haemorrhagic enteritis

proliferation

38
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parvoviral necrotic- haemorrhagic enteritis

proliferation
increased mitosis
marked: myotic figures

39
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parvoviral necrotic- haemorrhagic enteritis

payers patches

40
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parvoviral necrotic- haemorrhagic enteritis

center of lymphoid follicle
replicating lymphoid cells –> b-cells–> target for virus

41
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parvoviral necrotic- haemorrhagic enteritis

blue : muscularis
green : submucosa
red: serous membrane

above muscularis you can see that crypts and villi is missing –> necrosis

42
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parvoviral necrotic- haemorrhagic enteritis

villi and crypts is missing –> necrosis

43
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parvoviral necrotic- haemorrhagic enteritis

no recognizable epithelial tissue
–> necrosis

44
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acute purulent leptomeningitis
glaesserella parauis / streptococcus suis
glasser disease

pia mater is thickened

brain tissue is intact

45
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acute purulent leptomeningitis
glaesserella parauis / streptococcus suis
glasser disease

extremely dialated blood vesssel / microtrombus

46
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acute purulent leptomeningitis
glaesserella parauis / streptococcus suis
glasser disease

extremely dialated blood vessel / microthrombus

47
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acute purulent leptomeningitis
glaesserella parauis / streptococcus suis
glasser disease

inflammation purrulent : nutrophil granulocytes
thrombosis: with eosinic cells inside asweell

48
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acute purulent leptomeningitis
glaesserella parauis / streptococcus suis
glasser disease

inflammation purrulent : nutrophil granulocytes
thrombosis: with eosinic cells inside asweell

49
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Encephalitis caused by listeria monocytogenes

50
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Encephalitis caused by listeria monocytogenes

darker are is effected
meningis or pia mater is not thickened/ affected – key point to differentiate from glasser disease

51
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Encephalitis caused by listeria monocytogenes

lesion in brain = encephalitis
pia mater is not thickened

52
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Encephalitis caused by listeria monocytogenes

red: perivascular cuffing

blue: mononuclear

53
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Encephalitis caused by listeria monocytogenes

micro abcesses

nutrophils

54
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West Nile viral encephalitis

normal thick pia mater/meningis

55
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West Nile viral encephalitis

two types of lesion
one is connected to blood vessels and some is not

56
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West Nile viral encephalitis

extreme perivascular cuffing with mononuclear cells in multiple layers

57
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West Nile viral encephalitis

infects neurons –>. phagocytosis –> glial scarring

58
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West Nile viral encephalitis

infects neurons –>. phagocytosis –> glial scarring

glial scarring

59
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West Nile viral encephalitis

extreme perivascular cuffing with mononuclear cells in multiple layers

Histopathology (6 decks)

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