Histopathology Practical 1

Question 1

Which tissue is this and what is the structure in the middle?

Answer 1

Liver
Vena centralis

Question 2

What does the edges portal triad consist off?

Answer 2

A. Hepatica
V. Portae
Bileduct

Question 3

Answer 3

Microvesicular fatty infiltration
( steatohepatopathy)

Question 4

Answer 4

Macrovesicular fatty infiltration
(steatohepatopathy)

Question 5

Answer 5

Macrovesicular fatty infiltration
(steatohepatopathy)

more severe around central vein
some nuclei are in very bad shape
might effect function of liver cells

Question 6

Answer 6

Ionophor ( nicarbasin) toxicosis
muscle dystrophy

Question 7

Answer 7

Ionophor ( nicarbasin) toxicosis
muscle dystrophy

• macrophages try to remove necrotized area

Question 8

Answer 8

Ionophor ( nicarbasin) toxicosis
muscle dystrophy

Question 9

Answer 9

chronic demarcation
angiofibroblast tissue - early necrosis

Question 10

Answer 10

chronic demarcation

angiofibroblast tissue –> formation of new blood vessels

fibrocytes : flatter, darker

fibroblast: active cells rounder

more wavey tissue -> more mature tissue

Question 11

Answer 11

Tuberculum ( cattle lungs)

red: artery
blue : microbronchus
green : granuloma ( tubercule, after mycobacteria)

Question 12

Answer 12

langhans type multi nuclear giant cells

Question 13

Answer 13

black : neutrophil granulocytes
white: histiocytes

Question 14

Answer 14

calcium deposition
can only find it in mammals NEVER in poultry

Question 15

Answer 15

mycobacteria is stained red, ziehl nielsen staining

Question 16

when can fatty infiltration happen ?

Answer 16

stuffed geese
dogs with diabetes
cows that are lactation

Question 17

what can be seen in a tuberculum of cattle?
- foreign body type giant cell
- langerhans type giant cell
- all three can be seen
-langhans type giant cell

Answer 17

-langhans type giant cell

Question 18

What can be the cause of skeletal muscle dystrophy?
- Mycobacterium bovis
- vitamin E deficiency
- the rapid onset of lactation
- ionophore toxicosis

Answer 18

• ionophore toxicosis

Question 19

Is the macrovesicular steatohepathopathy a reversible lesion?
- Yes
- No
- Only if less than 50% of hepatic parenchyma is affected
- only if less than 30% of hepatic parenchyma is affected

Answer 19

• No

Question 20

Which statement is true for the tuberculum?
- it has a concentric structure
- all three answers are correct
- it is an epitheloid type granuloma
- it is caused by mycobacteria

Answer 20

• all three answers are correct

Question 21

What is the difference between microvesicular and macrovesicular steatohepathy?
- the size of vesicles
- all three
- the extent of cell damage
- the severity of the process

Answer 21

• all three

Question 22

What is necessary for fat staining in histopathology?
- Ziehl-Neelsen staining
- fixation in alcohol
- fixation in cold formaldehyde
- frozen sections

Answer 22

• frozen sections

Question 23

Calcification can be present in the centrum of a tubercule
- Right
- Wrong

Answer 23

right

Question 24

Mention mononuclear cells

Answer 24

Plasma cells
Lymphocytes
Macrophage