Histology of Urinary Tract Flashcards
Urinary tract epithelium is…
Transitional Epithelium / Urothelium
Transitional epithelium lines…
ureter,urethra, calyx, bladder
Transitional epithelium has a superficial layer containing… what type of cell?
Umbrella cells
Umbrella Cells
dome shaped cells, that have plaques to provide protection to the underlying cells against urine that has low ph
Uroplaques are…
lipid rafts containing integral membrane protein
that can ….
stretch when the bladder is filled with pee
Uroplaques or Uroplakins are…
lipid rafts containing integral membrane protein
that can ….
stretch when the bladder is filled with pee
Uroplakins by having tight junction serve as …
osmotic barries that protects cells from hypertonic urine and prevents dilution of stored urine
Urinary bladder consists of… what layers?
Mucosa: transitional epithelium,basement membrane, and lamina propia(connective fibroelastic tissue)
Submucosa
Muscularis: contains detrusor muscle (involuntary muscle)
Adventitia: function as protection and causes bladder to adhere to anterior abdominal wall (can be serosa)
What is the difference when we have an empty bladder vs a filled one? How can we tell if its empty or filled?
By the volumen of the urothelium , if epithelium is distenteded(flat cells) then the bladder ir filled
Muscular coat of urinary bladder is …
Detrusor Muscle
Detrusor Muscle is composed of…
longitudinal layer (thin)
circular layer (thick, middle)
longitudinal (thin)
Middle circular layer of Detrusor Muscle is composed of…
Elastic fibers
Bundle of elastic fiber in circular layer of detrusor muscle forms…
internal sphincter muscle
Internal Sphincter muscle is located….
around the internal orifice of the neck of the bladder
Ureter does NOT contain… what layer?
Submucosa layer
