Histology of the Skin Flashcards
This system of the bodyy is composed of the skin and epidermal derivatives
Intergumentary system
this part is the largets organ
- 15 bw
-
Skin
thinnest part of the skin
Eyelids
Thickest part of the Skin
Soles
This parts functions are protection from harmful substances entering the body
- regulate body tempt
- excretes waste
- Vit D
- individual identification
Skin
Is the skin a Sensory organ
True
What are the main layers of the Skin
- Epidermis
- Dermis
- Hypodermis
This layer of the skin is most superficial
Epidermis
this part of the skin is made up of Keratinized Squamous Epithelium
Epidermis
this part of the skin if derived from the ectoderm
Epidermis
Irregular conical invaginations that project into the dermis
Epidermal Ridges
this part of the skin is the deepest layer
Dermis
this part of the skin is composed of connective tissues
Dermis
this part of the skin if derived from the mesoderm
Dermis
Elements that project into the epidermis
Dermal Papillae
this part of the skin has connective tissues beneath the dermis
Hypodermis
this part of the skin connects underlying tissues
Hypodermis
this part of the skin usually skin appendages extend to
Hypodermis
These are layers of adipose tissue in individuals who are over nourished
Panniculus Adiposus
parts of the body where there are no adipose cells
- penis
- scrotum
- eyelids
- nipple
- areola
this part of the skin is renewed 20- 30 days
Epidermis
this part of the skin is classified as thick and thin
epidermis
This helps renew skin
Keratinocyte
principle cell of the epidermis
Keratinocyte
what does Keratinocyte produce
Keratin
these cells are in the deep layers of epridermis
slowly pushes out and undergoes keratinization
Keratinocyets
5 layers of thick skin
- startum germanitivum
- startum spinosum
- stratum granulosum
stratum lucidum - stratum corneum
Layers under Startum Malpighii
- startum germanitivum
- startum spinosum
- stratum granulosum
Layer of thick skin with cells composed of keratin fiber
Cornified layers
Cornified layers of the thick skin
- stratum lucidum
- stratum corneum
This thick skin layer is deepest to most superficial
Stratum Germinativum
what is S. Germinavitum composed of/ kind of cells
Tall cuboidal cells
Binds lateral surfaces
Desmosomes
Bind basal surface of cells to basal lamina
Hemidesmosomes
This thick skin layer has large nucleus with basophilic cytoplasm with numerous ribosomes
S. Germinativum
This thick skin layer contains polyhydral cells
– cells are mitotically active
S. Spinosum
S. Basale
S. germinativum
S. spinosum have the same cytoplasm content with this thick skin layer
S. germinativum
This thick skin layer tighly bound to neighbors desomosomes
S. Spinosum
under the LM they appear like spindles or spines between cells
s. Spinosum
This thick skin layer has to skin layers of flattened keratinocytes
s. granulosum
This thick skin layer has dead cells
and more flat than spinosum
s. granulosom
This thick skin layer cannot go under mitosis
s. granulosom
This thick skin layer has pyknotic nucles
s. granulosom
what is pyknotic nucles
flat nucleus
2 types of granules in the s. granulosom
- Keratohyalin granules
- secretory granules
Type of granule in the s. granulosom that is numerous and dark, no membrane and no keratin
contains profillagrin
Keratohyaline granules
whats profillagrin
histidine rich protein
type of granule in the s. granulosom that has lipids
- membrane bound
- closelyy packed lamella
- content is deposited in intercellular space
Secretory granules
This thick skin layer that has 4 to 6 layers
- dead cells
- anucleated cells
- cytoplasm
- has keratin
Stratum lucidum
This thick skin layer has 12 to 20 layer
- cytoplasm has keratin
- deeper cells with desmosomes
- horny cells
Stratum Corneum
Types of skin according to Thickness
- Thick skin
- Thin Skin
this type of skin has longer dermal papillae than thin
- has sweat glands and lacks hair follicles
- palms and soles
Thick skin
this type of skin has
- shorter dermal papillae
- has sweat glands and hair follicles
- whole body except soles and palms
Thin skin
this skin layer has all 5 layers present
Thick skin
this skin layer has spinosum,
no lucidum
poorly granulosom
Thin layer
Cells in the Epidermis
- keratinocytes
- Melanocytes
- Langerhans cells
- Merkel Cells
this cell in the epidermis is the pricipal cell for skin renewal
- keratin
- 85% to 95%
Keratinocytes