Histology of renal system Flashcards
whatre renal columns
inward extensions of cortical tissue, that separate pyramids
distribution of blood
cortex - 90%
medulla - 10%
what makes rena corpuscles
glomerulus
proximal segment of nephron
cortical labyrinths consist of
renal corpuscles
collecting tubules
convoluted tubules and nephrons
cortical nephron
have short loops of henle
located in upper part of cortex
what are juxtamedullary nephrons
renal corpuscles located at thebase of medullary pyramid
have long loops of henny
intermediate/midcortical nephrons
renal corpuscles located at midregion of cortex
bowmans capsule, external layer epithelial layer
simple squamous epithelium associated with connective tissue stroma
continuous with simple cuboidal epithelium of proximal convoluted tubule
visceral layer attaches to glomerulus
consists of podocytes reinforced by basal lamina
what does the renal corpuscle act as
acts as semi permeable membrane
endothelium of glomerular capillaries
contains fenestrations
fenestrations have no diaphragm
contains large number of aquaporins
components of filtration
endothelium of glomerular capillaries
glomerular basement membrane
visceral layer
layers of GBM
lamina rara interna - contains polyanions
lamina externa
lamina densa - contains type 4 collagen and sialoglycoproteins
mesangial cells functions
contractile phagocytic capable of proliferation synthesize both matrix and collagen structural support secrete prostaglandins and endothelins
juxtaglomerular apparatus consists of
macula densa
juxtaglomerular cells which produce renin
extraglomerular mesangial cells which regulate bp by activating renin angiotensin aldosterone system
functions of proximal tubule
major site of reabsorption
re absorbs amino acids, sugars and polypeptides
endocytoses proteins and large peptides
describe cuboidal cells of proximal convoluted tubes
brush border
plicae borders
inter digitation
basal striations
thin segment of loop of henle epithelial cells
type 1 - located in descending and ascending
type 2 - found in thin descending
type 3 - found in thin descending and medulla
type 4 - found at the bend
medullary loop functions
functions as counter current multiplier system to determine osmolarity
collecting ducts epithelium
collecting ducts - squamous to cuboidal
medullary collecting ducts - simple cuboidal to columnal
which renal artery is higher than the other
left,
right renal artery passes posterior to ivc
ureteric vasculature
upper end - renal arteries
middle - branches of abdominal aorta, testicular, ovarian, common iliac
pelvic cavity - internal iliac and its branches
ureter innervation
renal, aortic, superior hypogastric, inferior hypogastric plexuses
