Histology - Extracellular Matrix

Question 0

Enodcytosed hyaluronic cells function:

Answer 0

Has a role in maintaining space and modulating microtubular activities during the metaphase and anaphase stages of mitosis, thus facilitating chromosomal movements.

Intracellular roles may involve modulation of intracellular trafficking and influencing intracytoplasmic-specific and intranuclear-specific kinase

Question 1

Where are the GAGs synthesized?

Answer 1

All GAGs are synthesized within the golgi appartus by resident enzymes -exept hyaluronic acid, which is synthesized as a free linear polymer at the cytoplasmic face of the plasma membrane by hyaluronan synthases

Question 2

What type of bond is between the GAGs and the protein core?

Answer 2

Covalent bonds

Question 3

What is the most common connective tissue?

Answer 3

Connetive tissue proper

Question 4

ECM is composed of:

Answer 4

• Ground substance

- Fibers

Question 5

Ground substance

Answer 5

- Composed of: 
    > GAGs
    > Proteoglycans
    > Glycoproteins
- Resist forces of compression

Question 6

Fibers

Answer 6

- 3 types:
    > Collagen fibers
    > Reticular fibers
    > Elastic fibers
- Resist tensile forces